Recombinant Mouse IL-9 Protein, CF | R&D Systems 409-ML-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-9 Protein, CF

catalog :

409-ML-010/CF

quantity :

10 ug (also 50 ug)

price :

425 USD

citations: 11

Reference
Deng K, Yang X, Luo Q, She Y, Yu Q, Tang X. Deleterious Role of Th9 Cells in Pulmonary Fibrosis. Cells. 2021;10: pubmed publisher
Yashiro T, Ogata H, Zaidi S, Lee J, Hayashi S, Yamamoto T, et al. Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice. Cells. 2021;10: pubmed publisher
Liu X, Zhou F, Wang W, Chen G, Zhang Q, Lv R, et al. IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis. J Neuroinflammation. 2021;18:108 pubmed publisher
Almeida R, Vieira R, Castoldi A, Terra F, Melo A, Canesso M, et al. Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity. Br J Cancer. 2020;123:534-541 pubmed publisher
Liu N, Jiang Y, Chen J, Nan H, Zhao Y, Chu X, et al. IL-33 drives the antitumor effects of dendritic cells via the induction of Tc9 cells. Cell Mol Immunol. 2018;: pubmed publisher
Turner J, Morrison P, Wilhelm C, Wilson M, Ahlfors H, Renauld J, et al. IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med. 2013;210:2951-65 pubmed publisher
Purwar R, Schlapbach C, Xiao S, Kang H, Elyaman W, Jiang X, et al. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012;18:1248-53 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher
Vang K, Yang J, Mahmud S, Burchill M, Vegoe A, Farrar M. IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development. J Immunol. 2008;181:3285-90 pubmed
Reader J, Hyde D, Schelegle E, Aldrich M, Stoddard A, McLane M, et al. Interleukin-9 induces mucous cell metaplasia independent of inflammation. Am J Respir Cell Mol Biol. 2003;28:664-72 pubmed

product information

master code :

409-ML/CF

SKU :

409-ML-010/CF

product name :

Recombinant Mouse IL-9 Protein, CF

unit size :

10 ug (also 50 ug)

description :

The Recombinant Mouse IL-9 Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse IL-9 Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-9

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

Multiple bands between 16-25 kDa, reducing conditions

theoretical molecular weight :

14.2 kDa

gene symbol :

Il9

details of functionality :

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. Avanzi, G. et al . (1988) Br. J. Haematol. 69 :359. The ED50 for this effect is 0.500-5.00 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P15247

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse IL-9 protein Gln19-Pro144

source short :

Sf 21 (baculovirus)

USD :

425 USD

alt names :

Cytokine P40, HP40, IL9, IL-9homolog of mouse T cell and mast cell growth factor 40, interleukin 9, interleukin-9, P40, p40 cytokine, p40 T-cell and mast cell growth factor, T-cell growth factor P40

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.