Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF | R&D Systems 4055-CR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF

catalog :

4055-CR-050

quantity :

50 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Liu Y, Tang B, Lu M, Wang H. Astragaloside IV improves pulmonary arterial hypertension by increasing the expression of CCN1 and activating the ERK1/2 pathway. J Cell Mol Med. 2023;27:622-633 pubmed publisher
Won J, Choi J, Jun J. CCN1 interacts with integrins to regulate intestinal stem cell proliferation and differentiation. Nat Commun. 2022;13:3117 pubmed publisher
Imhof B, Jemelin S, Ballet R, Vesin C, Schapira M, Karaca M, et al. CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation. Proc Natl Acad Sci U S A. 2016;113:E4847-56 pubmed publisher
Comes S, Gagliardi M, Laprano N, Fico A, Cimmino A, Palamidessi A, et al. L-Proline induces a mesenchymal-like invasive program in embryonic stem cells by remodeling H3K9 and H3K36 methylation. Stem Cell Reports. 2013;1:307-21 pubmed publisher
Craig T, Bhattacharya R, Mukhopadhyay D, Kumar R. Sclerostin binds and regulates the activity of cysteine-rich protein 61. Biochem Biophys Res Commun. 2010;392:36-40 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

4055-CR

SKU :

4055-CR-050

product name :

Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF

Description :

The Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Cyr61/CCN1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Cyr61/CCN1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

70-75 kDa, reducing conditions

theoretical molecular weight :

66.3 kDa

gene symbol :

CYR61

details of functionality :

Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. Ball, D.K. et al . (2003) Reproduction 125 :271. Recombinant Human Cyr61/CCN1 Fc Chimera immobilized at 1.5 µg/mL, 100 µL/well, will mediate 25% BALB/3T3 cell adhesion (3 x 104 cell/well added).

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

O00622

applications :

Bioactivity

source :

CHO-derived Recombinant Human Cyr61/CCN1 Fc Chimera Protein

USD :

396 USD

alt names :

CCN family member 1, CCN1, CCN1IGF-binding protein 10, Cysteine-rich angiogenic inducer 61, cysteine-rich, angiogenic inducer, 61, GIG1, GIG1cysteine-rich heparin-binding protein 61, IBP-10, IGFBP-10, IGFBP10cysteine-rich, anigogenic inducer, 61, Insulin-like growth factor-binding protein 10, protein CYR61, Protein GIG1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage