Recombinant Human Integrin alpha M beta 2 Protein, CF | R&D Systems 4047-AM product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha M beta 2 Protein, CF

catalog :

4047-AM

quantity :

50 ug

price :

419 USD

citations: 3

Reference
Ayala Lujan J, Vijayakumar V, Gong M, Smith R, Santiago A, Ruiz Perez F. Broad spectrum activity of a lectin-like bacterial serine protease family on human leukocytes. PLoS ONE. 2014;9:e107920 pubmed publisher
Jerke U, Rolle S, Dittmar G, Bayat B, Santoso S, Sporbert A, et al. Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation. J Biol Chem. 2011;286:7070-81 pubmed publisher
Rao N, Argyle B, Xu X, Reynolds P, Walenga J, Prechel M, et al. Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands. Am J Physiol Cell Physiol. 2010;299:C97-110 pubmed publisher

product information

brand :

R&D Systems

master code :

4047-AM

SKU :

4047-AM-050

product name :

Recombinant Human Integrin alpha M beta 2 Protein, CF

description :

The Recombinant Human Integrin alpha M beta 2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha M beta 2 Protein, CF has been validated for the following applications: Bioactivity.

target :

Integrin alpha M beta 2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and MgCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

165 kDa and 100 kDa, reducing conditions

theoretical molecular weight :

124.7 kDa (Integrin alpha M), 79 kDa (Integrin beta 2)

gene symbol :

ITGAM

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with ICAM-1. The ED50 for this effect is 0.25-1.5 µg/mL.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

4047-AM

accessionNumbers :

NP_001139280 (Integrin alpha M) P05107 (Integrin beta 2)

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha M beta 2 protein Human Integrin alpha M (Phe17-Asn1105) Accession # NP_001139280 acidic tail Human Integrin beta 2 (Gln23-Asn700) Accession # P05107 basic tail N-terminus C-terminus

2020 USD :

398

2021 USD :

419 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.