Recombinant Human IBSP/Sialoprotein II Protein, CF | R&D Systems 4014-SP-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IBSP/Sialoprotein II Protein, CF

catalog :

4014-SP-050

quantity :

50 ug

price :

524 USD

citations: 6

Reference
Thuong L, Huang C, Fong Y, Liu C, Guo J, Wu C, et al. Bone sialoprotein facilitates anoikis resistance in lung cancer by inhibiting miR-150-5p expression. J Cell Mol Med. 2024;28:e70155 pubmed publisher
Umemoto A, Kuwada T, Murata K, Shiokawa M, Ota S, Murotani Y, et al. Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther. 2023;25:25 pubmed publisher
Ghochani Y, Muthukrishnan S, Sohrabi A, Kawaguchi R, Condro M, Bastola S, et al. A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration. Cell Rep. 2022;41:111511 pubmed publisher
White K, Cali V, Olabisi R. Micropatterning biomineralization with immobilized mother of pearl proteins. Sci Rep. 2021;11:2141 pubmed publisher
Barros N, Hoac B, Neves R, Addison W, Assis D, Murshed M, et al. Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia. J Bone Miner Res. 2013;28:688-99 pubmed publisher
Akter R, Rivas D, Geneau G, Drissi H, Duque G. Effect of lamin A/C knockdown on osteoblast differentiation and function. J Bone Miner Res. 2009;24:283-93 pubmed publisher

product information

master code :

4014-SP

SKU :

4014-SP-050

product name :

Recombinant Human IBSP/Sialoprotein II Protein, CF

unit size :

50 ug

description :

The Recombinant Human IBSP/Sialoprotein II Protein, CF from R&D Systems is derived from CHO. The Recombinant Human IBSP/Sialoprotein II Protein, CF has been validated for the following applications: Bioactivity.

target :

IBSP/Sialoprotein II

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

75-90 kDa, reducing conditions

theoretical molecular weight :

34.7 kDa

gene symbol :

IBSP

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of the MCF-7 human breast cancer cells. The ED50 of this effect is 0.0600 - 0.600 ╡g/mL

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAC95490

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human IBSP/Sialoprotein II protein Phe17-Gln317, with a C-terminal 10-His tag

source short :

CHO

USD :

524 USD

alt names :

BNSP, Bone sialoprotein, Bone sialoprotein 2, BSP, BSP 2, BSP II, BSP2, BSPII, BSP-II, Cell binding sialoprotein, IBSP, Integrin binding sialoprotein, SP II, SPII, SP-II

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.