Recombinant Rat Dkk-1 Protein, CF | R&D Systems 4010-DK-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Dkk-1 Protein, CF

catalog :

4010-DK-010/CF

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Zhang S, Yang Y, Jia S, Chen H, Duan Y, Li X, et al. Exosome-like vesicles derived from Hertwig's epithelial root sheath cells promote the regeneration of dentin-pulp tissue. Theranostics. 2020;10:5914-5931 pubmed publisher
Huang J, Bao Y, Xiang W, Jing X, Guo J, Yao X, et al. Icariin Regulates the Bidirectional Differentiation of Bone Marrow Mesenchymal Stem Cells through Canonical Wnt Signaling Pathway. Evid Based Complement Alternat Med. 2017;2017:8085325 pubmed publisher
Bao J, Ma C, Ran J, Xiong Y, Yan S, Wu L. Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes. Oncotarget. 2017;8:109962-109972 pubmed publisher
Kong X, Li X, Zhang C, Zhu L, Liu C, Qin Q, et al. Ethyl acetate fraction of Huogu formula inhibits adipogenic differentiation of bone marrow stromal cells via the BMP and Wnt signaling pathways. Int J Biol Sci. 2017;13:480-491 pubmed publisher
Cai T, Sun D, Duan Y, Wen P, Dai C, Yang J, et al. WNT/?-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression. Exp Cell Res. 2016;345:206-17 pubmed publisher
Smith A, Lewis F, Aquila I, Waring C, Nocera A, Agosti V, et al. Isolation and characterization of resident endogenous c-Kit+ cardiac stem cells from the adult mouse and rat heart. Nat Protoc. 2014;9:1662-81 pubmed publisher

image

image 1 :

Recombinant Rat Dkk-1 Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

4010-DK/CF

SKU :

4010-DK-010/CF

product name :

Recombinant Rat Dkk-1 Protein, CF

Description :

The Recombinant Rat Dkk-1 Protein, CF from R&D Systems is derived from NS0.

target :

Dkk-1

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Rat

observed molecular weight :

38-42 kDa, reducing conditions

theoretical molecular weight :

27.6 kDa

details of functionality :

Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. Recombinant Rat Dkk-1 inhibits a constant dose of 100 ng/mL of Recombinant Mouse Wnt-3a (Catalog # 1324-WN ). The ED50 for this effect is 50-300 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_001099820

source :

NS0-derived Recombinant Rat Dkk-1 Protein

USD :

423 USD

alt names :

dickkopf (Xenopus laevis) homolog 1, dickkopf homolog 1 (Xenopus laevis), dickkopf related protein-1, Dickkopf-1, dickkopf-related protein 1, Dkk1, DKK-1, hDkk-1, SKdickkopf-1 like

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage