Stancic A, Saksida T, Markelic M, Vucetic M, Grigorov I, Martinović V, et al. Ferroptosis as a Novel Determinant of β-Cell Death in Diabetic Conditions. Oxid Med Cell Longev. 2022;2022:3873420 pubmed publisher

Ma S, Patel S, Abe Y, Chen N, Patel P, Cho B, et al. RORγt phosphorylation protects against T cell-mediated inflammation. Cell Rep. 2022;38:110520 pubmed publisher

Miranda J, Schleicher W, Wells K, Ramirez D, Landgrave S, Benninger R. Dynamic changes in β-cell [Ca2+] regulate NFAT activation, gene transcription, and islet gap junction communication. Mol Metab. 2022;57:101430 pubmed publisher

Kaushik D, Bhattacharya A, Lozinski B, Wee Yong V. Pericytes as mediators of infiltration of macrophages in multiple sclerosis. J Neuroinflammation. 2021;18:301 pubmed publisher

Duan Y, Chu H, Brandl K, Jiang L, Zeng S, Meshgin N, et al. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease. Nat Commun. 2021;12:7172 pubmed publisher

Chauhan P, Sheng W, Hu S, Prasad S, Lokensgard J. Differential Cytokine-Induced Responses of Polarized Microglia. Brain Sci. 2021;11: pubmed publisher

Fu A, van Rooyen L, Evans L, Armstrong N, Avizonis D, Kin T, et al. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets. Cell Rep. 2021;37:110037 pubmed publisher

Shi Y, Li S, Zhang H, Zhu J, Che T, Yan B, et al. The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons. J Neuroinflammation. 2021;18:261 pubmed publisher

van de Wetering C, Manuel A, Sharafi M, Aboushousha R, Qian X, Erickson C, et al. Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2. Redox Biol. 2021;47:102160 pubmed publisher

Lee S, Ishitsuka A, Kuroki T, Lin Y, Shibuya A, Hongu T, et al. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes. JCI Insight. 2021;6: pubmed publisher

Dupraz L, Magniez A, Rolhion N, Richard M, Da Costa G, Touch S, et al. Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells. Cell Rep. 2021;36:109332 pubmed publisher

Chen E, Lee C, Thompson P, Wiest D, Anderson M, Zuniga Pflucker J. Ontogenic timing, T cell receptor signal strength, and Notch signaling direct γδ T cell functional differentiation in vivo. Cell Rep. 2021;35:109227 pubmed publisher

Han X, Xu T, Fang Q, Zhang H, Yue L, Hu G, et al. Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy. Redox Biol. 2021;44:102010 pubmed publisher

Singh A, Dashynam M, Chim B, Escobar T, Liu X, Hu X, et al. Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells. Sci Rep. 2021;11:11498 pubmed publisher

Farré Alins V, Palomino Antolin A, Narros Fernández P, López Rodríguez A, Decouty Pérez C, Muñoz Montero A, et al. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients. Biomedicines. 2021;9: pubmed publisher

Kwak D, Park D, Kim J. Leukotriene B4 Receptors Are Necessary for the Stimulation of NLRP3 Inflammasome and IL-1β Synthesis in Neutrophil-Dominant Asthmatic Airway Inflammation. Biomedicines. 2021;9: pubmed publisher

Lu Y, Liu L, Pan J, Luo B, Zeng H, Shao Y, et al. MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway. Cell Death Dis. 2021;12:533 pubmed publisher

Zhao J, Cai B, Shao Z, Zhang L, Zheng Y, Ma C, et al. TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1. Cell Death Differ. 2021;28:3077-3091 pubmed publisher

Grieshaber Bouyer R, Radtke F, Cunin P, Stifano G, Levescot A, Vijaykumar B, et al. The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments. Nat Commun. 2021;12:2856 pubmed publisher

Takahashi A, Aleyasin H, Stavarache M, Li L, Cathomas F, Parise L, et al. Neuromodulatory effect of interleukin 1β in the dorsal raphe nucleus on individual differences in aggression. Mol Psychiatry. 2021;: pubmed publisher

Clark H, McKenney C, Livingston N, Gershman A, Sajjan S, Chan I, et al. Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level. Nat Commun. 2021;12:1836 pubmed publisher

Shi H, Sun L, Wang Y, Liu A, Zhan X, Li X, et al. N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization. Nat Commun. 2021;12:1379 pubmed publisher

Micheli L, Vasarri M, Barletta E, Lucarini E, Ghelardini C, Degl Innocenti D, et al. Efficacy of Posidonia oceanica Extract against Inflammatory Pain: In Vivo Studies in Mice. Mar Drugs. 2021;19: pubmed publisher

Yang Y, Shen P, Yao T, Ma J, Chen Z, Zhu J, et al. Novel role of circRSU1 in the progression of osteoarthritis by adjusting oxidative stress. Theranostics. 2021;11:1877-1900 pubmed publisher

Sanmarco L, Wheeler M, Gutiérrez Vázquez C, Polonio C, Linnerbauer M, Pinho Ribeiro F, et al. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature. 2021;: pubmed publisher

Yao X, Sun K, Yu S, Luo J, Guo J, Lin J, et al. Chondrocyte ferroptosis contribute to the progression of osteoarthritis. J Orthop Translat. 2021;27:33-43 pubmed publisher

Engler A, Ysasi A, Pihl R, Villacorta Martin C, Heston H, Richardson H, et al. Airway-Associated Macrophages in Homeostasis and Repair. Cell Rep. 2020;33:108553 pubmed publisher

Nummenmaa E, Hamalainen M, Pemmari A, Moilanen L, Tuure L, Nieminen R, et al. Transient Receptor Potential Ankyrin 1 (TRPA1) Is Involved in Upregulating Interleukin-6 Expression in Osteoarthritic Chondrocyte Models. Int J Mol Sci. 2020;22: pubmed publisher

Shamdani S, Chantepie S, Flageollet C, Henni Chebra N, Jouan Y, Eymard F, et al. Heparan sulfate functions are altered in the osteoarthritic cartilage. Arthritis Res Ther. 2020;22:283 pubmed publisher

Lee S, Kim S, Kang H, Lim H, Kwon Y, Jo M, et al. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response. J Neuroinflammation. 2020;17:299 pubmed publisher

Namai F, Shigemori S, Ogita T, Sato T, Shimosato T. Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice. Exp Mol Med. 2020;52:1627-1636 pubmed publisher

Grubisic V, McClain J, Fried D, Grants I, Rajasekhar P, Csizmadia E, et al. Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation. Cell Rep. 2020;32:108100 pubmed publisher

Maqbool M, Pioger L, El Aabidine A, Karasu N, Molitor A, Dao L, et al. Alternative Enhancer Usage and Targeted Polycomb Marking Hallmark Promoter Choice during T Cell Differentiation. Cell Rep. 2020;32:108048 pubmed publisher

Mizoguchi I, Ohashi M, Hasegawa H, Chiba Y, Orii N, Inoue S, et al. EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin. J Clin Invest. 2020;130:6124-6140 pubmed publisher

Kwiecien K, Brzoza P, Bak M, Majewski P, Skulimowska I, Bednarczyk K, et al. The methylation status of the chemerin promoter region located from - 252 to + 258 bp regulates constitutive but not acute-phase cytokine-inducible chemerin expression levels. Sci Rep. 2020;10:13702 pubmed publisher

Liu M, Yan M, Lv H, Wang B, Lv X, Zhang H, et al. Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis. Cell Rep. 2020;32:107990 pubmed publisher

Osthues T, Zimmer B, Rimola V, Klann K, Schilling K, Mathoor P, et al. The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain. Cells. 2020;9: pubmed publisher

Dong Y, Li S, Lu Y, Li X, Liao Y, Peng Z, et al. Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice. J Neuroinflammation. 2020;17:205 pubmed publisher

Hanschmann E, Petry S, Eitner S, Maresch C, Lingwal N, Lillig C, et al. Paracrine regulation and improvement of β-cell function by thioredoxin. Redox Biol. 2020;34:101570 pubmed publisher

Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, et al. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Cell Death Dis. 2020;11:377 pubmed publisher

Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, et al. Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nat Cell Biol. 2020;22:716-727 pubmed publisher

Ma S, Zhang A, Li X, Zhang S, Liu S, Zhao H, et al. MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1. Arthritis Res Ther. 2020;22:99 pubmed publisher

Chien S, Tsai C, Liu S, Huang C, Lin T, Yang Y, et al. Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis. Cells. 2020;9: pubmed publisher

Haidar O, O Neill N, Staunton C, Bavan S, O Brien F, Zouggari S, et al. Pro-inflammatory Cytokines Drive Deregulation of Potassium Channel Expression in Primary Synovial Fibroblasts. Front Physiol. 2020;11:226 pubmed publisher

Shimo T, Takebe H, Okui T, Kunisada Y, Ibaragi S, Obata K, et al. Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing. Int J Mol Sci. 2020;21: pubmed publisher

Son H, Lee J, Lee H, Kim N, Jo Y, Lee G, et al. Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 β expression. Acta Pharm Sin B. 2020;10:462-474 pubmed publisher

Li H, Ding X, Terkeltaub R, Lin H, Zhang Y, Zhou B, et al. Exploration of metformin as novel therapy for osteoarthritis: preventing cartilage degeneration and reducing pain behavior. Arthritis Res Ther. 2020;22:34 pubmed publisher

Wheeler M, Clark I, Tjon E, Li Z, Zandee S, Couturier C, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. 2020;578:593-599 pubmed publisher

Simões F, Cahill T, Kenyon A, Gavriouchkina D, Vieira J, Sun X, et al. Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair. Nat Commun. 2020;11:600 pubmed publisher

Ichii M, Oritani K, Toda J, Saito H, Shi H, Shibayama H, et al. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress. Haematologica. 2020;: pubmed publisher

Jang J, Kim D, Lim J, Lee J, Jeong S, Kim K, et al. Breast Cancer Cell-Derived Soluble CD44 Promotes Tumor Progression by Triggering Macrophage IL1β Production. Cancer Res. 2020;80:1342-1356 pubmed publisher

van de Wetering C, Aboushousha R, Manuel A, Chia S, Erickson C, Macpherson M, et al. Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease. J Immunol. 2020;204:763-774 pubmed publisher

Lee H, Kim L, Choi J. NFAT-Specific Inhibition by dNP2-VIVITAmeliorates Autoimmune Encephalomyelitisby Regulation of Th1 and Th17. Mol Ther Methods Clin Dev. 2020;16:32-41 pubmed publisher

Pan P, Zhang Q, Liu W, Wang W, Yu Z, Lao Z, et al. Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage. Front Microbiol. 2019;10:2637 pubmed publisher

Pham D, Moseley C, Gao M, Savic D, Winstead C, Sun M, et al. Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf. Cell Rep. 2019;29:1203-1220.e7 pubmed publisher

Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed publisher

Ji D, Yamashiro L, Chen K, Mukaida N, Kramnik I, Darwin K, et al. Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra. Nat Microbiol. 2019;4:2128-2135 pubmed publisher

Yu J, Zhu H, Taheri S, Mondy W, Bonilha L, Magwood G, et al. Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia. J Neurosci. 2019;39:9465-9476 pubmed publisher

Zammit N, Walters S, Seeberger K, O Connell P, Korbutt G, Grey S. A20 as an immune tolerance factor can determine islet transplant outcomes. JCI Insight. 2019;4: pubmed publisher

Bensellam M, Chan J, Lee K, Joglekar M, Hardikar A, Loudovaris T, et al. Phlda3 regulates beta cell survival during stress. Sci Rep. 2019;9:12827 pubmed publisher

Chan T, Yen C, Huang Y, Lo P, Nigrovic P, Cheng C, et al. Increased ILC3s associated with higher levels of IL-1β aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase. Eur J Immunol. 2019;49:2063-2073 pubmed publisher

Chen G, Luo X, Wang W, Wang Y, Zhu F, Wang W. Interleukin-1β Promotes Schwann Cells De-Differentiation in Wallerian Degeneration via the c-JUN/AP-1 Pathway. Front Cell Neurosci. 2019;13:304 pubmed publisher

Darkwah S, Nago N, Appiah M, Myint P, Kawamoto E, Shimaoka M, et al. Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis. Biomedicines. 2019;7: pubmed publisher

Lao C, Zhou X, Chen H, Wei F, Huang Z, Bai C. 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt. Bioorg Chem. 2019;90:103077 pubmed publisher

Zhou X, Chen H, Wei F, Zhao Q, Su Q, Liang J, et al. 3β-Acetyloxy-oleanolic Acid Attenuates Pristane-Induced Lupus Nephritis by Regulating Th17 Differentiation. J Immunol Res. 2019;2019:2431617 pubmed publisher

Lalwani A, Warren J, Liuwantara D, Hawthorne W, O Connell P, Gonzalez F, et al. β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes. Cell Rep. 2019;27:2370-2384.e6 pubmed publisher

Kim D, Park H, Park H, Lee J, Ko C, Gye M, et al. Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity. Exp Mol Med. 2019;51:41 pubmed publisher

Finucane O, Sugrue J, Rubio Araiz A, Guillot Sestier M, Lynch M. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages. Sci Rep. 2019;9:4034 pubmed publisher

Liu Y, Song Y, Lin D, Lei L, Mei Y, Jin Z, et al. NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development. EBioMedicine. 2019;41:333-344 pubmed publisher

Morita Takemura S, Nakahara K, Hasegawa Ishii S, Isonishi A, Tatsumi K, Okuda H, et al. Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance. J Neuroinflammation. 2019;16:39 pubmed publisher

Glenn J, Liu C, Whartenby K. Frontline Science: Induction of experimental autoimmune encephalomyelitis mobilizes Th17-promoting myeloid derived suppressor cells to the lung. J Leukoc Biol. 2019;105:829-841 pubmed publisher

Lee H, Lee J, Kim D, Lim S, Kang I, Choi J. Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis. Nat Commun. 2019;10:709 pubmed publisher

Li W, Zhao S, Yang H, Zhang C, Kang Q, Deng J, et al. Potential Novel Prediction of TMJ-OA: MiR-140-5p Regulates Inflammation Through Smad/TGF-β Signaling. Front Pharmacol. 2019;10:15 pubmed publisher

Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, et al. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation. Nat Commun. 2019;10:549 pubmed publisher

Saeki Y, Ishiyama K, Ishida N, Tanaka Y, Ohdan H. Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation. Sci Rep. 2019;9:1022 pubmed publisher

Das S, Bar Sagi D. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis. Oncogene. 2019;38:3316-3324 pubmed publisher

Kolb R, Kluz P, Tan Z, Borcherding N, Bormann N, Vishwakarma A, et al. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4. Oncogene. 2019;38:2351-2363 pubmed publisher

Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher

Dou F, Chu X, Zhang B, Liang L, Lu G, Ding J, et al. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-κB signaling pathway. Mol Brain. 2018;11:75 pubmed publisher

Engelowski E, Modares N, Gorressen S, Bouvain P, Semmler D, Alter C, et al. IL-23R Signaling Plays No Role in Myocardial Infarction. Sci Rep. 2018;8:17078 pubmed publisher

Mathies F, Steffens N, Kleinschmidt D, Stuhlmann F, Huber F, Roy U, et al. Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells. J Immunol. 2018;201:3558-3568 pubmed publisher

de Lima K, Donate P, Talbot J, Davoli Ferreira M, Peres R, Cunha T, et al. TGFβ1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism. Cell Death Dis. 2018;9:1130 pubmed publisher

Berger C, Crepin V, Roumeliotis T, Wright J, Serafini N, Pevsner Fischer M, et al. The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses. PLoS Pathog. 2018;14:e1007406 pubmed publisher

Benjamin J, Moore D, Bennett C, Van Der Meer R, Royce A, Loveland R, et al. Cutting Edge: IL-1α and Not IL-1β Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality. J Immunol. 2018;201:2873-2878 pubmed publisher

Nam H, Nam J, Yoon G, Lee J, Nam Y, Kang H, et al. Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice. J Neuroinflammation. 2018;15:271 pubmed publisher

Ballak D, Li S, Cavalli G, Stahl J, Tengesdal I, van Diepen J, et al. Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue. J Biol Chem. 2018;293:14224-14236 pubmed publisher

Hsieh C, Lin C, He J, Chiang M, Wang Y, Tsai Y, et al. Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice. Stem Cell Res Ther. 2018;9:183 pubmed publisher

Seeley J, Baker R, Mohamed G, Bruns T, Hayden M, Deshmukh S, et al. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors. Nature. 2018;559:114-119 pubmed publisher

Skelly D, Griffin E, Murray C, Harney S, O Boyle C, Hennessy E, et al. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms. Mol Psychiatry. 2018;: pubmed publisher

Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed publisher

Caughron B, Yang Y, Young M. Role of IL-23 signaling in the progression of premalignant oral lesions to cancer. PLoS ONE. 2018;13:e0196034 pubmed publisher

Kuwata H, Yuzurihara C, Kinoshita N, Taki Y, Ikegami Y, Washio S, et al. The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts. FEBS J. 2018;285:2056-2070 pubmed publisher

Meyer zu Horste G, Przybylski D, Schramm M, Wang C, Schnell A, Lee Y, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48:556-569.e7 pubmed publisher

Lin H, Wang J, Wang J, Li W, Wang X, Alston J, et al. GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function. Mol Metab. 2018;11:205-211 pubmed publisher

St Leger A, Hansen A, Karauzum H, Horai R, Yu C, Laurence A, et al. STAT-3-independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection. J Exp Med. 2018;215:1079-1090 pubmed publisher

Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed publisher

Wang Q, Lv S, Guo Y, Duan J, Dong S, Wang Q, et al. Pharmacological Effect of Caulophyllum robustum on Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-κB, and Proinflammatory Cytokines In Vivo and In Vitro. Evid Based Complement Alternat Med. 2017;2017:8134321 pubmed publisher

Klement W, Garbelli R, Zub E, Rossini L, Tassi L, Girard B, et al. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature. Neurobiol Dis. 2018;113:70-81 pubmed publisher

Song A, Zhu L, Gorantla G, Berdysz O, Amici S, Guerau de Arellano M, et al. Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells. Sci Rep. 2018;8:723 pubmed publisher

Mancini A, Tantucci M, Mazzocchetti P, de Iure A, Durante V, Macchioni L, et al. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis. Neurobiol Dis. 2018;113:97-108 pubmed publisher

Makino H, Seki S, Yahara Y, Shiozawa S, Aikawa Y, Motomura H, et al. A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain. Sci Rep. 2017;7:16983 pubmed publisher

Smith S, Samokhin A, Alfadi M, Murphy E, Rhodes D, Holcombe W, et al. The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease. JACC Basic Transl Sci. 2017;2:398-414 pubmed publisher

Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed publisher

Kamizaki K, Doi R, Hayashi M, Saji T, Kanagawa M, Toda T, et al. The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle. J Biol Chem. 2017;292:15939-15951 pubmed publisher

Nordmann T, Dror E, Schulze F, Traub S, Berishvili E, Barbieux C, et al. The Role of Inflammation in β-cell Dedifferentiation. Sci Rep. 2017;7:6285 pubmed publisher

Haim Y, Bluher M, Konrad D, Goldstein N, Kloting N, Harman Boehm I, et al. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype. Mol Metab. 2017;6:725-736 pubmed publisher

Wang C, Xu C, Alippe Y, Qu C, Xiao J, Schipani E, et al. Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells. Sci Rep. 2017;7:4880 pubmed publisher

Nam S, Kim K, Kim M, Jang J, Rah S, Chae H, et al. Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan. Pharm Biol. 2017;55:1856-1862 pubmed publisher

Mufazalov I, Kuschmann J, Andruszewski D, Masri J, Gabriel L, Adams P, et al. Balanced Bcl-3 expression in murine CD4+ T cells is required for generation of encephalitogenic Th17 cells. Eur J Immunol. 2017;47:1335-1341 pubmed publisher

Zhao Q, Harbour S, Kolde R, Latorre I, Tun H, Schoeb T, et al. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. J Immunol. 2017;199:312-322 pubmed publisher

Yang A, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, et al. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017;127:2829-2841 pubmed publisher

Ledesma Colunga M, Adán N, Ortiz G, Solís Gutiérrez M, Lopez Barrera F, Martinez de la Escalera G, et al. Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis. Arthritis Res Ther. 2017;19:93 pubmed publisher

Yi C, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, et al. TNFα drives mitochondrial stress in POMC neurons in obesity. Nat Commun. 2017;8:15143 pubmed publisher

Reverchon F, Mortaud S, Sivoyon M, Maillet I, Laugeray A, Palomo J, et al. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria. PLoS Pathog. 2017;13:e1006322 pubmed publisher

Wang K, Ye L, Lu H, Chen H, Zhang Y, Huang Y, et al. TNF-? promotes extracellular vesicle release in mouse astrocytes through glutaminase. J Neuroinflammation. 2017;14:87 pubmed publisher

Li M, Zheng H, Luo Y, He J, Wang W, Han J, et al. Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs. Mol Psychiatry. 2018;23:556-568 pubmed publisher

Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, et al. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017;214:1453-1469 pubmed publisher

Sireesh D, Ganesh M, Dhamodharan U, Sakthivadivel M, Sivasubramanian S, Gunasekaran P, et al. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade. J Nutr Biochem. 2017;44:11-21 pubmed publisher

LaRock C, Todd J, LaRock D, Olson J, O Donoghue A, Robertson A, et al. IL-1β is an innate immune sensor of microbial proteolysis. Sci Immunol. 2016;1: pubmed publisher

Lee M, McCubbin J, Christensen A, Poole D, Rajasekhar P, Lieu T, et al. G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease. J Immunol. 2017;198:3565-3575 pubmed publisher

Jiang F, Meng D, Weng M, Zhu W, Wu W, Kasper D, et al. The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1β-induced inflammation in human fetal enterocytes via toll receptors 2 and 4. PLoS ONE. 2017;12:e0172738 pubmed publisher

Di Candia L, Gomez E, Venereau E, Chachi L, Kaur D, Bianchi M, et al. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4. J Allergy Clin Immunol. 2017;140:584-587.e8 pubmed publisher

Huang W, Fan W, Wang Y, Han D, Li X, Li S, et al. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway. Cell Death Discov. 2017;3:16097 pubmed publisher

Franchi L, Monteleone I, Hao L, Spahr M, Zhao W, Liu X, et al. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. J Immunol. 2017;198:2735-2746 pubmed publisher

Choi S, You S, Kim D, Choi S, Kwon H, Kim H, et al. Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis. J Clin Invest. 2017;127:954-969 pubmed publisher

Ciavarra R, Lundberg P, Machida M, Ambrozewicz M, Wellman L, Breving K, et al. Early gene activation initiates neuroinflammation prior to VSV neuroinvasion: Impact on antiviral responses and sleep. J Neuroimmunol. 2017;303:31-42 pubmed publisher

Itani S, Watanabe T, Nadatani Y, Sugimura N, Shimada S, Takeda S, et al. NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis. Sci Rep. 2016;6:39075 pubmed publisher

Xue X, Soroosh P, De Leon Tabaldo A, Luna Roman R, Sablad M, Rozenkrants N, et al. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis. Sci Rep. 2016;6:37977 pubmed publisher

Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher

Urrutia M, Fernandez S, Gonzalez M, Vilches R, Rojas P, Vásquez M, et al. Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels. PLoS ONE. 2016;11:e0163735 pubmed publisher

Mishra A, Guo Y, Zhang L, More S, Weng T, Chintagari N, et al. A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury. J Immunol. 2016;197:2828-37 pubmed publisher

He X, Qian Y, Li Z, Fan E, Li Y, Wu L, et al. TLR4-Upregulated IL-1? and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism. Sci Rep. 2016;6:31663 pubmed publisher

Raguz J, Jerić I, Niault T, Nowacka J, Kuzet S, Rupp C, et al. Epidermal RAF prevents allergic skin disease. elife. 2016;5: pubmed publisher

Ibiza S, García Cassani B, Ribeiro H, Carvalho T, Almeida L, Marques R, et al. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 2016;535:440-443 pubmed publisher

Michel M, Lenoir C, Massot B, Diem S, Pasquier B, Sawa S, et al. SLAM-associated protein favors the development of iNKT2 over iNKT17 cells. Eur J Immunol. 2016;46:2162-74 pubmed publisher

Guthrie L, Abiraman K, Plyler E, Sprenkle N, Gibson S, McFarland B, et al. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses. J Biol Chem. 2016;291:15830-40 pubmed publisher

Verrier T, Satoh Takayama N, Serafini N, Marie S, Di Santo J, Vosshenrich C. Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells. J Immunol. 2016;196:4731-8 pubmed publisher

Zuchtriegel G, Uhl B, Puhr Westerheide D, Pörnbacher M, Lauber K, Krombach F, et al. Platelets Guide Leukocytes to Their Sites of Extravasation. PLoS Biol. 2016;14:e1002459 pubmed publisher

Pasi S, Kant R, Surolia A. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response. J Biol Chem. 2016;291:12358-69 pubmed publisher

Swaroop S, Sengupta N, Suryawanshi A, Adlakha Y, Basu A. HSP60 plays a regulatory role in IL-1β-induced microglial inflammation via TLR4-p38 MAPK axis. J Neuroinflammation. 2016;13:27 pubmed publisher

Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, et al. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol. 2015;195:4415-25 pubmed publisher

Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, et al. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nat Med. 2015;21:363-72 pubmed publisher

Liu X, Yamashita T, Chen Q, Belevych N, McKim D, Tarr A, et al. Interleukin 1 type 1 receptor restore: a genetic mouse model for studying interleukin 1 receptor-mediated effects in specific cell types. J Neurosci. 2015;35:2860-70 pubmed publisher

Annemann M, Wang Z, Plaza Sirvent C, Glauben R, Schuster M, Ewald Sander F, et al. IκBNS regulates murine Th17 differentiation during gut inflammation and infection. J Immunol. 2015;194:2888-98 pubmed publisher

Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, et al. Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis. J Immunol. 2015;194:2522-30 pubmed publisher

Basu R, Whitley S, Bhaumik S, Zindl C, Schoeb T, Benveniste E, et al. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance. Nat Immunol. 2015;16:286-95 pubmed publisher

Cowardin C, Kuehne S, Buonomo E, Marie C, Minton N, Petri W. Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. MBio. 2015;6: pubmed publisher

Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, et al. Direct conversion of fibroblasts into functional astrocytes by defined transcription factors. Stem Cell Reports. 2015;4:25-36 pubmed publisher

Lutz A, Sanwald J, Thomas M, Feuer R, Sawodny O, Ederer M, et al. Interleukin-1β enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes. PLoS ONE. 2014;9:e115603 pubmed publisher

Jin S, Sonobe Y, Kawanokuchi J, Horiuchi H, Cheng Y, Wang Y, et al. Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells. PLoS ONE. 2014;9:e115981 pubmed publisher

Dunne A, Mielke L, Allen A, Sutton C, Higgs R, Cunningham C, et al. A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. Mucosal Immunol. 2015;8:607-17 pubmed publisher

Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, et al. Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway. elife. 2014;3:e02809 pubmed publisher

Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med. 2014;211:1807-19 pubmed publisher

Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T. Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2?. J Immunol. 2014;193:1459-67 pubmed publisher

Ingham V, Williams A, Bate C. Glimepiride reduces CD14 expression and cytokine secretion from macrophages. J Neuroinflammation. 2014;11:115 pubmed publisher

Glenn J, Smith M, Calabresi P, Whartenby K. Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis. Stem Cells. 2014;32:2744-55 pubmed publisher

Bakker P, Butter L, Claessen N, Teske G, Sutterwala F, Florquin S, et al. A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion. Am J Pathol. 2014;184:2013-22 pubmed publisher

Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, et al. Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gin. J Biol Chem. 2014;289:15621-30 pubmed publisher

Tamiya H, Terao M, Takiuchi T, Nakahara M, Sasaki Y, Katayama I, et al. IFN-? or IFN-? ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex. J Immunol. 2014;192:3793-804 pubmed publisher

Hahn W, Kuzmicic J, Burrill J, Donoghue M, Foncea R, Jensen M, et al. Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Am J Physiol Endocrinol Metab. 2014;306:E1033-45 pubmed publisher

Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh Hora M, Kodama T, et al. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med. 2014;20:62-8 pubmed publisher

Lee S, Lee K, Yi S, Kook S, Lee J. Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-?B pathway and attenuating ROS production. PLoS ONE. 2013;8:e80873 pubmed publisher

Halai K, Whiteford J, Ma B, Nourshargh S, Woodfin A. ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo. J Cell Sci. 2014;127:620-9 pubmed publisher

Zehendner C, Wedler H, Luhmann H. A novel in vitro model to study pericytes in the neurovascular unit of the developing cortex. PLoS ONE. 2013;8:e81637 pubmed publisher

Jana M, Mondal S, Jana A, Pahan K. Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology. 2014;141:549-63 pubmed publisher

Moon C, VanDussen K, Miyoshi H, Stappenbeck T. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal Immunol. 2014;7:818-28 pubmed publisher

Valcarcel M, Carrascal T, Crende O, Vidal Vanaclocha F. IL-18 regulates melanoma VLA-4 integrin activation through a Hierarchized sequence of inflammatory factors. J Invest Dermatol. 2014;134:470-480 pubmed publisher

Steelman A, Smith R, Welsh C, Li J. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis. J Biol Chem. 2013;288:23776-87 pubmed publisher

Schmid M, Franco I, Kang S, Hirsch E, Quilliam L, Varner J. PI3-kinase ? promotes Rap1a-mediated activation of myeloid cell integrin ?4?1, leading to tumor inflammation and growth. PLoS ONE. 2013;8:e60226 pubmed publisher

Jayaraman P, Sada Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, et al. IL-1? promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation. J Immunol. 2013;190:4196-204 pubmed publisher

Song J, Wu C, Zhang X, Sorokin L. In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1?-induced peritonitis. J Immunol. 2013;190:401-10 pubmed publisher

Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Vegran F, et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med. 2013;19:57-64 pubmed publisher

Willart M, Deswarte K, Pouliot P, Braun H, Beyaert R, Lambrecht B, et al. Interleukin-1? controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J Exp Med. 2012;209:1505-17 pubmed publisher

Flanagan K, FITZGERALD K, Baker J, Regnstrom K, Gardai S, Bard F, et al. Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. PLoS ONE. 2012;7:e40443 pubmed publisher

Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher

Zhao H, Zhao X, Cao X, Wu G. Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice. Immun Ageing. 2012;9:12 pubmed publisher

Proebstl D, Voisin M, Woodfin A, Whiteford J, D Acquisto F, Jones G, et al. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo. J Exp Med. 2012;209:1219-34 pubmed publisher

Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, et al. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1? regulation of FXR expression. Mol Endocrinol. 2012;26:775-85 pubmed publisher

Quinton L, Blahna M, Jones M, Allen E, Ferrari J, Hilliard K, et al. Hepatocyte-specific mutation of both NF-?B RelA and STAT3 abrogates the acute phase response in mice. J Clin Invest. 2012;122:1758-63 pubmed publisher

Dubin P, Martz A, Eisenstatt J, Fox M, Logar A, Kolls J. Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection. Infect Immun. 2012;80:398-409 pubmed publisher

El Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol. 2011;12:568-75 pubmed publisher

Ma Y, Aymeric L, Locher C, Mattarollo S, Delahaye N, Pereira P, et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med. 2011;208:491-503 pubmed publisher

Sanchez Alavez M, Osborn O, Tabarean I, Holmberg K, Eberwine J, Kahn C, et al. Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptors. J Biol Chem. 2011;286:14983-90 pubmed publisher

Owyang A, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, et al. XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases. MAbs. 2011;3:49-60 pubmed

Petri B, Kaur J, Long E, Li H, Parsons S, Butz S, et al. Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood. 2011;117:942-52 pubmed publisher

Jayaraman P, Sada Ovalle I, Beladi S, Anderson A, Dardalhon V, Hotta C, et al. Tim3 binding to galectin-9 stimulates antimicrobial immunity. J Exp Med. 2010;207:2343-54 pubmed publisher

Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, et al. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus. J Virol. 2010;84:12703-12 pubmed publisher

Chou R, Kim N, Sadik C, Seung E, Lan Y, Byrne M, et al. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis. Immunity. 2010;33:266-78 pubmed publisher

Cho J, Pietras E, Garcia N, Ramos R, Farzam D, Monroe H, et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest. 2010;120:1762-73 pubmed publisher

Grossberg A, Scarlett J, Zhu X, Bowe D, Batra A, Braun T, et al. Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130. Endocrinology. 2010;151:606-16 pubmed publisher

Ohno T, Oboki K, Kajiwara N, Morii E, Aozasa K, Flavell R, et al. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages. J Immunol. 2009;183:7890-7 pubmed publisher

Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff Mueser U, Lampa J, et al. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept. Brain Behav Immun. 2010;24:747-58 pubmed publisher

Chen X, Fang L, Song S, Guo T, Liu A, Zhang J. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway. J Immunol. 2009;183:6135-44 pubmed publisher

Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med. 2009;15:1170-8 pubmed publisher

Martin U, Scholler J, Gurgel J, Renshaw B, Sims J, Gabel C. Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages. J Immunol. 2009;183:4021-30 pubmed publisher

Mizutani N, Nabe T, Yoshino S. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. J Immunol. 2009;183:4039-46 pubmed publisher

Koziczak Holbro M, Littlewood Evans A, Pöllinger B, Kovarik J, Dawson J, Zenke G, et al. The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation. Arthritis Rheum. 2009;60:1661-71 pubmed publisher

Nilsberth C, Elander L, Hamzic N, Norell M, Lönn J, Engström L, et al. The role of interleukin-6 in lipopolysaccharide-induced fever by mechanisms independent of prostaglandin E2. Endocrinology. 2009;150:1850-60 pubmed publisher

Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, et al. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs. Arthritis Rheum. 2008;58:3510-9 pubmed publisher

Scarlett J, Zhu X, Enriori P, Bowe D, Batra A, Levasseur P, et al. Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation. Endocrinology. 2008;149:4837-45 pubmed publisher

Hudson C, Christophi G, Gruber R, Wilmore J, Lawrence D, Massa P. Induction of IL-33 expression and activity in central nervous system glia. J Leukoc Biol. 2008;84:631-43 pubmed publisher

Bujak M, Dobaczewski M, Chatila K, Mendoza L, Li N, Reddy A, et al. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol. 2008;173:57-67 pubmed publisher

Wu C, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson D, et al. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell Immunol. 2008;251:78-85 pubmed publisher

Olivadoti M, Opp M. Effects of i.c.v. administration of interleukin-1 on sleep and body temperature of interleukin-6-deficient mice. Neuroscience. 2008;153:338-48 pubmed publisher

Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong M, et al. IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8. J Neurochem. 2008;105:1960-9 pubmed publisher

Antonopoulos C, Cumberbatch M, Mee J, Dearman R, Wei X, Liew F, et al. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis. J Leukoc Biol. 2008;83:361-7 pubmed

Kang Y, Kim S, Shimada S, Otsuka M, Seit Nebi A, Kwon B, et al. Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat Immunol. 2007;8:601-9 pubmed

Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H. Protection of CD8+ T cells from activation-induced cell death by IL-18. J Leukoc Biol. 2007;82:142-51 pubmed

Penido C, Conte F, Chagas M, Rodrigues C, Pereira J, Henriques M. Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice. Inflamm Res. 2006;55:457-64 pubmed

Shchors K, Shchors E, Rostker F, Lawlor E, Brown Swigart L, Evan G. The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta. Genes Dev. 2006;20:2527-38 pubmed

Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, et al. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model. J Mol Cell Cardiol. 2006;41:885-92 pubmed

Osuchowski M, Welch K, Siddiqui J, Remick D. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality. J Immunol. 2006;177:1967-74 pubmed

Vickers T, Zhang H, Graham M, Lemonidis K, Zhao C, Dean N. Modification of MyD88 mRNA splicing and inhibition of IL-1beta signaling in cell culture and in mice with a 2'-O-methoxyethyl-modified oligonucleotide. J Immunol. 2006;176:3652-61 pubmed

Mendez M, Morris S, Wilcoxen S, Greeson E, Moore B, Paine R. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2006;290:L962-70 pubmed

Ojaniemi M, Liljeroos M, Harju K, Sormunen R, Vuolteenaho R, Hallman M. TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice. Immunol Lett. 2006;102:158-68 pubmed

Osuchowski M, Siddiqui J, Copeland S, Remick D. Sequential ELISA to profile multiple cytokines from small volumes. J Immunol Methods. 2005;302:172-81 pubmed

Ellaban E, Bolgos G, Remick D. Selective macrophage suppression during sepsis. Cell Immunol. 2004;231:103-11 pubmed

Perrin F, Lacroix S, Avilés Trigueros M, David S. Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration. Brain. 2005;128:854-66 pubmed

Ching S, He L, Lai W, Quan N. IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system. Brain Behav Immun. 2005;19:127-37 pubmed