Recombinant Human CCL18/PARC Protein | R&D Systems 394-PA product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL18/PARC Protein

catalog :

394-PA

quantity :

10 ug (also 50 ug)

price :

299 USD

citations: 9

Reference
Barsheshet Y, Wildbaum G, Levy E, Vitenshtein A, Akinseye C, Griggs J, et al. CCR8+FOXp3+ Treg cells as master drivers of immune regulation. Proc Natl Acad Sci U S A. 2017;114:6086-6091 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Deegan P, Pavlova E, Tindall J, Stein P, Bearcroft P, Mehta A, et al. Osseous manifestations of adult Gaucher disease in the era of enzyme replacement therapy. Medicine (Baltimore). 2011;90:52-60 pubmed publisher
Pavlova E, Deegan P, Tindall J, McFarlane I, Mehta A, Hughes D, et al. Potential biomarkers of osteonecrosis in Gaucher disease. Blood Cells Mol Dis. 2011;46:27-33 pubmed publisher
Leick M, Catusse J, Follo M, Nibbs R, Hartmann T, Veelken H, et al. CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B. Immunology. 2010;129:536-46 pubmed publisher
Chang C, Lee Y, Leu S, Wang C, Wei C, Hung K, et al. CC-chemokine ligand 18/pulmonary activation-regulated chemokine expression in the CNS with special reference to traumatic brain injuries and neoplastic disorders. Neuroscience. 2010;165:1233-43 pubmed publisher
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Günther C, Bello Fernandez C, Kopp T, Kund J, Carballido Perrig N, Hinteregger S, et al. CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells. J Immunol. 2005;174:1723-8 pubmed
Wan Y, Jakway J, Qiu H, Shah H, Garlisi C, Tian F, et al. Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002;456:1-10 pubmed

product information

brand :

R&D Systems

master code :

394-PA

SKU :

394-PA-010

product name :

Recombinant Human CCL18/PARC Protein

description :

The Recombinant Human CCL18/PARC Protein from R&D Systems is derived from E. coli. The Recombinant Human CCL18/PARC Protein has been validated for the following applications: Bioactivity.

target :

CCL18/PARC

category :

Proteins and Enzymes

unit size :

10 ug (also 50 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

7.8 kDa

gene symbol :

CCL18

details of functionality :

Measured by its ability to inhibit Eotaxin-induced chemotaxis of BaF3 mouse pro-B cells transfected with human CCR3. Nibbs, RJB. et al . (2000) J. Immunol. 164 :1488. The ED50 for this effect is 1-5 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

394-PA

accessionNumbers :

P55774.1

applications :

Bioactivity

source :

E. coli -derived human CCL18/PARC protein Ala21-Ala89

2020 USD :

299

2021 USD :

299 USD

alt names :

Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1CC chemokine ligand 18, AMAC-1Small-inducible cytokine A18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), CKb7, DC-CK1, DC-CK1CC chemokine PARC, DCCK1Macrophage inflammatory protein 4, Dendritic cell chemokine 1, MIP4, MIP-4, MIP-4C-C motif chemokine 18, PARC, PARCPulmonary and activation-regulated chemokine, SCYA18chemokine (C-C), dendritic, small inducible cytokine A18, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated

storage :

12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.