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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CCL18/PARC Protein, CF
catalog :
394-PA-010/CF
quantity :
10 ug (also 50 ug)
price :
340 USD
more info or order :
R&D Systems product webpage
citations: 11
Reference
Huang Y, Motta E, Nanvuma C, Kuhrt L, Yuan Y, Xia P, et al. Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model. Cell Rep. 2022;39:110670 pubmed publisher
Jamal Jameel K, Gallert W, Yanik S, Panek S, Kronsbein J, Jungck D, et al. Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD. Int J Mol Sci. 2021;22: pubmed publisher
Amniai L, Ple C, Barrier M, de Nadai P, Marquillies P, Vorng H, et al. Natural Killer Cells from Allergic Donors Are Defective in Their Response to CCL18 Chemokine. Int J Mol Sci. 2021;22: pubmed publisher
Barsheshet Y, Wildbaum G, Levy E, Vitenshtein A, Akinseye C, Griggs J, et al. CCR8+FOXp3+ Treg cells as master drivers of immune regulation. Proc Natl Acad Sci U S A. 2017;114:6086-6091 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Deegan P, Pavlova E, Tindall J, Stein P, Bearcroft P, Mehta A, et al. Osseous manifestations of adult Gaucher disease in the era of enzyme replacement therapy. Medicine (Baltimore). 2011;90:52-60 pubmed publisher
Pavlova E, Deegan P, Tindall J, McFarlane I, Mehta A, Hughes D, et al. Potential biomarkers of osteonecrosis in Gaucher disease. Blood Cells Mol Dis. 2011;46:27-33 pubmed publisher
Leick M, Catusse J, Follo M, Nibbs R, Hartmann T, Veelken H, et al. CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B. Immunology. 2010;129:536-46 pubmed publisher
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Günther C, Bello Fernandez C, Kopp T, Kund J, Carballido Perrig N, Hinteregger S, et al. CCL18 is expressed in atopic dermatitis and mediates skin homing of human memory T cells. J Immunol. 2005;174:1723-8 pubmed
Wan Y, Jakway J, Qiu H, Shah H, Garlisi C, Tian F, et al. Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding. Eur J Pharmacol. 2002;456:1-10 pubmed
product information
brand :
R&D Systems
master code :
394-PA/CF
SKU :
394-PA-010/CF
product name :
Recombinant Human CCL18/PARC Protein, CF
description :
The Recombinant Human CCL18/PARC Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human CCL18/PARC Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL18/PARC
category :
Proteins and Enzymes
sizes available :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile with Trehalose.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
7.8 kDa
gene symbol :
CCL18
details of functionality :
Measured by its ability to inhibit Eotaxin-induced chemotaxis of BaF3 mouse pro-B cells transfected with human CCR3. Nibbs, RJB. et al . (2000) J. Immunol. 164 :1488. The ED50 for this effect is 1-5 µg/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P55774.1
applications :
Bioactivity
source :
E. coli-derived Recombinant Human CCL18/PARC Protein, CF
USD :
334
USD 2023 :
340 USD
alt names :
Alternative macrophage activation-associated CC chemokine 1, AMAC-1, AMAC1CC chemokine ligand 18, AMAC-1Small-inducible cytokine A18, chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated), CKb7, DC-CK1, DC-CK1CC chemokine PARC, DCCK1Macrophage inflammatory protein 4, Dendritic cell chemokine 1, MIP4, MIP-4, MIP-4C-C motif chemokine 18, PARC, PARCPulmonary and activation-regulated chemokine, SCYA18chemokine (C-C), dendritic, small inducible cytokine A18, small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary andactivation-regulated
storage :
12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.