product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CXCL7/NAP-2 Protein
catalog :
393-NP-010
quantity :
10 ug (also 50 ug)
price :
282 USD
more info or order :
citations: 7
Reference
Egan K, van Geffen J, Ma H, Kevane B, Lennon A, Allen S, et al. Effect of platelet-derived β-thromboglobulins on coagulation. Thromb Res. 2017;154:7-15 pubmed publisher
Laarman A, Mijnheer G, Mootz J, van Rooijen W, Ruyken M, Malone C, et al. Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis. EMBO J. 2012;31:3607-19 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Kirouac D, Ito C, Csaszar E, Roch A, Yu M, Sykes E, et al. Dynamic interaction networks in a hierarchically organized tissue. Mol Syst Biol. 2010;6:417 pubmed publisher
Fan X, Patera A, Pong Kennedy A, Deno G, Gonsiorek W, Manfra D, et al. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem. 2007;282:11658-66 pubmed
Smith C, Damås J, Otterdal K, Øie E, Sandberg W, Yndestad A, et al. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation. J Am Coll Cardiol. 2006;48:1591-9 pubmed
Traves S, Smith S, Barnes P, Donnelly L. Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2. J Leukoc Biol. 2004;76:441-50 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
393-NP
SKU :
393-NP-010
product name :
Recombinant Human CXCL7/NAP-2 Protein
Description :
The Recombinant Human CXCL7/NAP-2 Protein from R&D Systems is derived from E. coli.
target :
CXCL7/NAP-2
category :
Proteins and Enzymes
unit size :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
7.6 kDa
gene symbol :
PPBP
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 0.200-1.60 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P02775
source :
E. coli-derived Recombinant Human CXCL7/NAP-2 Protein
USD :
282 USD
alt names :
Beta-TG, connective tissue-activating peptide III, CTAP III, CTAP3CTAP-III, CTAPIII, CXC chemokine ligand 7, C-X-C motif chemokine 7, CXCL7b-TG1, LA-PF4, LDGFTC1, Leukocyte-derived growth factor, low-affinity platelet factor IV, Macrophage-derived growth factor, MDGFTC2, NAP2, NAP-2, NAP-2-L1, neutrophil-activating peptide 2, neutrophil-activating peptide-2, PBPTHBGB, platelet basic protein, PPBP, pro-platelet basic protein (chemokine (C-X-C motif) ligand 7), SCAR10, SCYB7beta-thromboglobulin, small inducible cytokine B7, small inducible cytokine subfamily B, member 7, Small-inducible cytokine B7, TGB, TGB1B-TG1, THBGB1, thrombocidin 1, thrombocidin 2, thromboglobulin, beta-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.