Recombinant Human IGF-I R/IGF1R Protein, CF | R&D Systems 391-GR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IGF-I R/IGF1R Protein, CF

catalog :

391-GR

quantity :

50 ug

price :

379 USD

citations: 4

Reference
Akla B, Broussas M, Loukili N, Robert A, Beau Larvor C, Malissard M, et al. Efficacy of the Antibody-Drug Conjugate W0101 in Preclinical Models of IGF-1 Receptor Overexpressing Solid Tumors. Mol Cancer Ther. 2020;19:168-177 pubmed publisher
Cedano Prieto D, Cheng Y, Chang C, Yu J, Takada Y, Takada Y. Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling. PLoS ONE. 2017;12:e0184285 pubmed publisher
Henry K, Sulea T, van Faassen H, Hussack G, Purisima E, Mackenzie C, et al. A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies. PLoS ONE. 2016;11:e0163113 pubmed publisher
Bäck K, Arnqvist H. Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes. Growth Horm IGF Res. 2009;19:101-11 pubmed publisher

product information

brand :

R&D Systems

master code :

391-GR

SKU :

391-GR-050

product name :

Recombinant Human IGF-I R/IGF1R Protein, CF

description :

The Recombinant Human IGF-I R/IGF1R Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IGF-I R/IGF1R Protein, CF has been validated for the following applications: Binding Activity.

target :

IGF-I R/IGF1R

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

160 kDa, 125 kDa, 50 kDa 40 kDa, reducing conditions

theoretical molecular weight :

102.9 kDa (single chain); 81.0 kDa ( alpha chain) 21.9 kDa ( beta chain)

gene symbol :

IGF1R

details of functionality :

Measured by its ability to bind human IGF-I R/IGF1R in a functional ELISA.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

391-GR

accessionNumbers :

P08069

applications :

Binding Activity

source :

Mouse myeloma cell line, NS0-derived human IGF-I R/IGF1R protein Met1-Asn932

2020 USD :

379

2021 USD :

379 USD

alt names :

CD221, CD221 antigen, EC 2.7.10, EC 2.7.10.1, IGF1R, IGF-1R, IGF-I receptor, IGFIR, IGF-IR, IGFR, insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, JTK13, MGC142170, MGC142172, MGC18216, soluble IGF1R variant 1, soluble IGF1R variant 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.