This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Proprotein Convertase 9/PCSK9 Protein, CF
catalog :
3888-SE
quantity :
10 ug
price :
339 USD
citations: 1
Reference
Rashid S, Tavori H, Brown P, Linton M, He J, Giunzioni I, et al. Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms. Circulation. 2014;130:431-41 pubmed publisher
product information
brand :
R&D Systems
master code :
3888-SE
SKU :
3888-SE-010
product name :
Recombinant Human Proprotein Convertase 9/PCSK9 Protein, CF
description :
The Recombinant Human Proprotein Convertase 9/PCSK9 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Proprotein Convertase 9/PCSK9 Protein, CF has been validated for the following applications: Bioactivity.
target :
Proprotein Convertase 9/PCSK9
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in Tris, NaCl and Glycerol.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
19 kDa 66 kDa, reducing conditions
theoretical molecular weight :
14 kDa 59 kDa
gene symbol :
PCSK9
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human LDL R (Catalog # 2148-LD ) is coated at 2 µg/mL, Recombinant Human Proprotein Convertase 9/PCSK9 binds with an ED50 of 70-420 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
3888-SE
accessionNumbers :
Q8NBP7
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human Proprotein Convertase 9/PCSK9 protein Gln31-Gln152 & Ser153-Gln692, with a C-terminal 10-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC1, NARC-1, NARC-1convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.