Recombinant Human FGF-22 Protein | R&D Systems 3867-FG-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-22 Protein

catalog :

3867-FG-025

quantity :

25 ug

price :

420 USD

citations: 5

Reference
Costa R, Martins H, Martins L, Cwetsch A, Mele M, Pedro J, et al. Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons. Cell Rep. 2019;28:864-876.e6 pubmed publisher
Westphal S, Gantert T, Kless C, Hüttinger K, Klingenspor M, Fromme T. Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Sci Rep. 2019;9:8470 pubmed publisher
Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, et al. Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10. Mol Cell Biol. 2014;34:2848-56 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher

product information

master code :

3867-FG

SKU :

3867-FG-025

product name :

Recombinant Human FGF-22 Protein

unit size :

25 ug

description :

The Recombinant Human FGF-22 Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF-22 Protein has been validated for the following applications: Bioactivity.

target :

FGF-22

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MES, Na2SO4, EDTA, Sucrose and DTT with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane.

species :

Human

theoretical molecular weight :

18 kDa

gene symbol :

FGF22

details of functionality :

Measured in a cell proliferation assay using 4MBr-5 rhesus monkey epithelial cells. Rubin, J.S. et al . (1989) Proc. Natl. Acad. Sci. USA 86 :802. The ED50 for this effect is 50-300 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9HCT0

applications :

Bioactivity

source long :

E. coli -derived human FGF-22 protein Thr23-Ser170, with an N-terminal Met and 6-His tag

source short :

E. coli

USD :

420 USD

alt names :

FGF22, FGF-22, fibroblast growth factor 22

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.