product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PDGF R beta Fc Chimera Protein
catalog :
385-PR-100
quantity :
100 ug
price :
458 USD
more info or order :
citations: 13
Reference |
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Ding K, Eaton L, Bowley D, Rieser M, Chang Q, Harris M, et al. Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration. MAbs. 2017;9:269-284 pubmed publisher
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Lacoste E, Martineau I, Gagnon G. Platelet concentrates: effects of calcium and thrombin on endothelial cell proliferation and growth factor release. J Periodontol. 2003;74:1498-507 pubmed
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product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
385-PR
SKU :
385-PR-100
product name :
Recombinant Human PDGF R beta Fc Chimera Protein
Description :
The Recombinant Human PDGF R beta Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human PDGF R beta Fc Chimera Protein has been validated for the following applications: Bioactivity.
target :
PDGF R beta
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
94-124 kDa, reducing conditions
theoretical molecular weight :
84 kDa (monomer)
gene symbol :
PDGFRB
details of functionality :
Measured by its ability to inhibit the biological activity of PDGF-BB using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 1-3 µg/mL in the presence of 50 ng/mL Recombinant Human PDGF-BB (Catalog # 220-BB ) .
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P09619
applications :
Bioactivity
source :
NS0-derived Recombinant Human PDGF R beta Fc Chimera Protein
USD :
458 USD
alt names :
beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140b, CD140b antigen, EC 2.7.10, EC 2.7.10.1, JTK12, PDGFR, PDGFR1, PDGFRB, PDGF-R-beta, platelet-derived growth factor receptor, beta polypeptide
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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