Recombinant Human Common gamma Chain Protein, CF | R&D Systems 384-RG-050/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Common gamma Chain Protein, CF

catalog :

384-RG-050/CF

quantity :

50 ug

price :

428 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Vincent M, Teppaz G, Lajoie L, Solé V, Bessard A, Maillasson M, et al. Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse. MAbs. 2014;6:1026-37 pubmed
Rose T, Lambotte O, Pallier C, Delfraissy J, Colle J. Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients. J Immunol. 2009;182:7389-97 pubmed publisher

product information

brand :

R&D Systems

master code :

384-RG/CF

SKU :

384-RG-050/CF

product name :

Recombinant Human Common gamma Chain Protein, CF

description :

The Recombinant Human Common gamma Chain Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Common gamma Chain Protein, CF has been validated for the following applications: Bioactivity.

target :

Common gamma Chain/IL-2 R gamma

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

40 kDa, reducing conditions

theoretical molecular weight :

28.2 kDa

gene symbol :

IL2RG

details of functionality :

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is typically 0.6-3.6 µg/mL in the presence of 30 µg/mL of soluble IL-2 R beta and 10 ng/mL of recombinant human IL-2.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P31785

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Human Common gamma Chain Protein, CF

USD :

421

USD 2023 :

428 USD

alt names :

CD132, CD132 antigen, CIDX, combined immunodeficiency, X-linked, common cytokine receptor gamma chain, common gamma-chain, cytokine receptor common subunit gamma, gamma(c), IL-2 R gamma, IL-2 receptor subunit gamma, IL2R gamma, IL-2R subunit gamma, IL2RG, IL-2RG, IMD4, interleukin 2 receptor, gamma, Interleukin-2 receptor subunit gamma, p64, SCIDX, SCIDX1, severe combined immunodeficiency

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage