Recombinant Human CD27/TNFRSF7 Fc Chimera Protein, CF | R&D Systems 382-CD-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD27/TNFRSF7 Fc Chimera Protein, CF

catalog :

382-CD-100

quantity :

100 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Fierle J, Abram Saliba J, Brioschi M, deTiani M, Coukos G, Dunn S. Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery. Sci Rep. 2019;9:12815 pubmed publisher
Silence K, Dreier T, Moshir M, Ulrichts P, Gabriels S, Saunders M, et al. ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade. MAbs. 2014;6:523-32 pubmed publisher
Yun L, Decarlo A, Hunter N. Blockade of protease-activated receptors on T cells correlates with altered proteolysis of CD27 by gingipains of Porphyromonas gingivalis. Clin Exp Immunol. 2007;150:217-29 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

382-CD

SKU :

382-CD-100

product name :

Recombinant Human CD27/TNFRSF7 Fc Chimera Protein, CF

Description :

The Recombinant Human CD27/TNFRSF7 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD27/TNFRSF7 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD27/TNFRSF7

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

60-70 kDa, reducing conditions

theoretical molecular weight :

46.5 kDa (monomer)

gene symbol :

CD27

details of functionality :

Measured by its ability to inhibit the proliferation of mouse T cells induced by CD27 Ligand and anti-CD3. The ED50 for this effect is 0.75-3 µg/mL in the presence of 10 µg/mL (100 µL/well) Recombinant Mouse CD27 Ligand/TNFSF7 (Catalog # 783-CL ) and anti-CD3.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P26842

applications :

Bioactivity

source :

NS0-derived Recombinant Human CD27/TNFRSF7 Fc Chimera Protein

USD :

423 USD

alt names :

CD27, CD27 antigen, CD27 molecule, MGC20393, S152CD27L receptor, T cell activation antigen CD27, T cell activation antigen S152, T14, TNFRSF7, TNFRSF7T-cell activation antigen CD27, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage