product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse M-CSF R/CD115 Fc Chimera Protein, CF
catalog :
3818-MR-050
quantity :
50 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Lundgren H, Martinsson K, Cederbrant K, Jirholt J, Mucs D, Madeyski Bengtson K, et al. HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity. PLoS ONE. 2017;12:e0184744 pubmed publisher
Yu H. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis. PLoS ONE. 2016;11:e0156303 pubmed publisher
Shimo T, Matsumoto K, Takabatake K, Aoyama E, Takebe Y, Ibaragi S, et al. The Role of Sonic Hedgehog Signaling in Osteoclastogenesis and Jaw Bone Destruction. PLoS ONE. 2016;11:e0151731 pubmed publisher
product information
master code :
3818-MR
SKU :
3818-MR-050
product name :
Recombinant Mouse M-CSF R/CD115 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse M-CSF R/CD115 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse M-CSF R/CD115 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
M-CSF R/CD115
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
115-135 kDa, reducing conditions
theoretical molecular weight :
82.3 kDa (monomer)
details of functionality :
Measured by its ability to inhibit the M-CSF-induced proliferation of M-NFS-60 mouse myelogenous leukemia lymphoblast cells. Halenbeck, R. et al . (1989) Biotechnology 7 :710. The ED50 for this effect is 0.2-0.8 ╡g/mL in the presence of 10 ng/mL mouse M-CSF.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P09581
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse M-CSF R/CD115 protein Mouse M-CSF R (Ala20-Ser511) Accession #P09581 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
456 USD
alt names :
CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, CSF1R, CSF-1-R, CSFR, EC 2.7.10.1, FMS proto-oncogene, FMSFIM2, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, MCSFR, M-CSFR, Proto-oncogene c-Fms
storage :
12 months from date of receipt, <= -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, <= -20 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.