Recombinant Human Integrin alpha V beta 6 Protein, CF | R&D Systems 3817-AV product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha V beta 6 Protein, CF

catalog :

3817-AV

quantity :

50 ug

price :

369 USD

citations: 4

Reference
Bönig T, Olbermann P, Bats S, Fischer W, Josenhans C. Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains. Sci Rep. 2016;6:38101 pubmed publisher
Shimmon G, Wood B, Morris A, Mioulet V, Grazioli S, Brocchi E, et al. Truncated Bovine Integrin Alpha-v/Beta-6 as a Universal Capture Ligand for FMD Diagnosis. PLoS ONE. 2016;11:e0160696 pubmed publisher
Barbariga M, Curnis F, Spitaleri A, Andolfo A, Zucchelli C, Lazzaro M, et al. Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling. J Biol Chem. 2014;289:3736-48 pubmed publisher
Curnis F, Cattaneo A, Longhi R, Sacchi A, Gasparri A, Pastorino F, et al. Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching. J Biol Chem. 2010;285:9114-23 pubmed publisher

product information

brand :

R&D Systems

master code :

3817-AV

SKU :

3817-AV-050

product name :

Recombinant Human Integrin alpha V beta 6 Protein, CF

description :

The Recombinant Human Integrin alpha V beta 6 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha V beta 6 Protein, CF has been validated for the following applications: Binding Activity.

target :

Integrin alpha V beta 6

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and CaCl2.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

145 kDa and 115 kDa, reducing conditions

theoretical molecular weight :

110.5 kDa ( alpha V subunit), 78.6 kDa ( beta 6 subunit)

gene symbol :

ITGAV

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Integrin alpha V beta 6 at 2.0 µg/mL can bind Recombinant Human LAP TGF-beta 1 (Catalog # 246-LP ) with an apparent Kd 0.1 nM.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

3817-AV

accessionNumbers :

NP_002201.1 (Integrin alpha V) P18564 (Integrin beta 6)

applications :

Binding Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha V beta 6 protein Human Integrin alpha V (Phe31-Val992) Accession # NP_002201.1 His-Pro GGGSGGGS Acidic Tail Human Integrin beta 6 (Gly22-Asn707) Accession # P18564 His-His-Pro GGGSGGGS Basic Tail N-terminus C-terminus

2020 USD :

369

2021 USD :

369 USD

alt names :

CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.