Recombinant Human Integrin alpha V beta 6 Protein, CF | R&D Systems 3817-AV-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha V beta 6 Protein, CF

catalog :

3817-AV-050

quantity :

50 ug

price :

421 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Bieri M, Hendrickx R, Bauer M, Yu B, Jetzer T, Dreier B, et al. The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection. PLoS Pathog. 2021;17:e1010083 pubmed publisher
Bönig T, Olbermann P, Bats S, Fischer W, Josenhans C. Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains. Sci Rep. 2016;6:38101 pubmed publisher
Shimmon G, Wood B, Morris A, Mioulet V, Grazioli S, Brocchi E, et al. Truncated Bovine Integrin Alpha-v/Beta-6 as a Universal Capture Ligand for FMD Diagnosis. PLoS ONE. 2016;11:e0160696 pubmed publisher
Barbariga M, Curnis F, Spitaleri A, Andolfo A, Zucchelli C, Lazzaro M, et al. Oxidation-induced structural changes of ceruloplasmin foster NGR motif deamidation that promotes integrin binding and signaling. J Biol Chem. 2014;289:3736-48 pubmed publisher
Curnis F, Cattaneo A, Longhi R, Sacchi A, Gasparri A, Pastorino F, et al. Critical role of flanking residues in NGR-to-isoDGR transition and CD13/integrin receptor switching. J Biol Chem. 2010;285:9114-23 pubmed publisher

product information

brand :

R&D Systems

master code :

3817-AV

SKU :

3817-AV-050

product name :

Recombinant Human Integrin alpha V beta 6 Protein, CF

unit size :

50 ug

description :

The TSPAN1 Antibody (819202) [PerCP] from Novus Biologicals is a mouse monoclonal antibody to TSPAN1. This antibody reacts with human. The TSPAN1 Antibody (819202) [PerCP] has been validated for the following applications: Flow Cytometry.

target :

Integrin alpha V beta 6

category :

Proteins and Enzymes

alt names :

CD51, integrin subunit alpha V, ITGAV, MSK8, VNRA, VTNR

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and CaCl2.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

145 kDa and 115 kDa, reducing conditions

theoretical molecular weight :

110.5 kDa ( alpha V subunit), 78.6 kDa ( beta 6 subunit)

gene symbol :

ITGAV

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Integrin alpha V beta 6 at 2.0 µg/mL can bind Recombinant Human LAP TGF-beta 1 (Catalog # 246-LP ) with an apparent Kd 0.1 nM.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_002201.1 (Integrin alpha V) P18564 (Integrin beta 6)

applications :

Binding Activity

source :

CHO-derived Recombinant Human Integrin alpha V beta 6 Protein, CF

USD :

389

Jul-22 :

421 USD

sizes available :

50 ug

more info or order :

R&D Systems product webpage