Recombinant Human Aminopeptidase N/CD13 Protein, CF | R&D Systems 3815-ZN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Aminopeptidase N/CD13 Protein, CF

catalog :

3815-ZN-010

quantity :

10 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
Papareddy P, Rossnagel M, Doreen Hollwedel F, Kilic G, Veerla S, Naudin C, et al. A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection. Nat Microbiol. 2019;4:2442-2455 pubmed publisher
Du Y, Lu C, Morgan R, Stinson W, Campbell P, Cealey E, et al. Angiogenic and Arthritogenic Properties of the Soluble Form of CD13. J Immunol. 2019;: pubmed publisher
Morgan R, Behbahani Nejad N, Endres J, Amin M, Lepore N, Du Y, et al. Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes. PLoS ONE. 2016;11:e0162008 pubmed publisher
Fiddler C, Parfrey H, Cowburn A, Luo D, Nash G, Murphy G, et al. The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion. PLoS ONE. 2016;11:e0160108 pubmed publisher
Sanz Garcia C, Nagy L, Lasunción M, Fernandez M, Alemany S. Cot/tpl2 participates in the activation of macrophages by adiponectin. J Leukoc Biol. 2014;95:917-30 pubmed publisher
Wilk S, Jenke A, Stehr J, Yang C, Bauer S, Göldner K, et al. Adiponectin modulates NK-cell function. Eur J Immunol. 2013;43:1024-33 pubmed publisher
Veillard F, Saidi A, Burden R, Scott C, Gillet L, Lecaille F, et al. Cysteine cathepsins S and L modulate anti-angiogenic activities of human endostatin. J Biol Chem. 2011;286:37158-67 pubmed publisher

image

image 1 :

Recombinant Human Aminopeptidase N/CD13 Protein Enzyme Activity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3815-ZN

SKU :

3815-ZN-010

product name :

Recombinant Human Aminopeptidase N/CD13 Protein, CF

Description :

The Recombinant Human Aminopeptidase N/CD13 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Aminopeptidase N/CD13 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Aminopeptidase N/CD13

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

131 kDa, reducing conditions

theoretical molecular weight :

104 kDa

gene symbol :

ANPEP

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Ala-7-amido-4-methylcoumarin (Ala-AMC). The specific activity is 2,500 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_001141

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Aminopeptidase N/CD13 Protein

USD :

423 USD

alt names :

alanyl (membrane) aminopeptidase, Alanyl aminopeptidase, Aminopeptidase M, aminopeptidase N, ANPEP, AP-M, APN, AP-N, CD13, CD13 antigen, CD13APN, EC 3.4.11, EC 3.4.11.2, gp150, LAP1, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, P150, PEPN, PEPNhAPN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage