product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Active PLK1 Protein, CF
catalog :
3804-KS-010
quantity :
10 ug
price :
534 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Mouery R, Lukasik K, Hsu C, Bonacci T, Bolhuis D, Wang X, et al. Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton. Cell Rep. 2024;43:114510 pubmed publisher
Fletcher C, Taylor M, Bevan C. PLK1 Regulates MicroRNA Biogenesis through Drosha Phosphorylation. Int J Mol Sci. 2023;24: pubmed publisher
Kim J, Kim E, Oh J, Park I, Hwang S. CIP2A modulates cell-cycle progression in human cancer cells by regulating the stability and activity of Plk1. Cancer Res. 2013;73:6667-78 pubmed publisher
product information
master code :
3804-KS
SKU :
3804-KS-010
product name :
Recombinant Human Active PLK1 Protein, CF
unit size :
10 ug
description :
The Recombinant Human Active PLK1 Protein, CF from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human Active PLK1 Protein, CF has been validated for the following applications: Bioactivity.
target :
PLK1
category :
Proteins and Enzymes
buffer :
Supplied in 50 mM Sodium Phosphate (pH 7.0), 300 mM NaCl, 150 mM Imidazole, 0.1 mM PMSF, 0.25 mM DTT, and 25% Glycerol.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie« Blue stain at 5 ╡g per lane.
species :
Human
observed molecular weight :
70 kDa
gene symbol :
PLK1
details of functionality :
The specific activity of PLK1 was equivalent to 42 nmol/min/mg as per Activity Assay Protocol and was equivalent to 17 nmol/min/mg as per radiometric assay.
top caption :
Recombinant Human Active PLK1 Protein SDS-PAGE
accessionNumbers :
NM_005030
applications :
Bioactivity
source long :
Spodoptera frugiperda , Sf 9 (baculovirus)-derived human PLK1 protein
source short :
Sf 9 (baculovirus)
USD :
534 USD
alt names :
cell cycle regulated protein kinase, EC 2.7.11, EC 2.7.11.21, PLK, PLK-1, polo (Drosophia)-like kinase, polo like kinase, polo-like kinase 1polo-like kinase (Drosophila), Serine/threonine-protein kinase 13, serine/threonine-protein kinase PLK1, STPK13
storage :
This product is stable at Avoid repeated freeze-thaw cycles.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.