Recombinant Human Methionine Aminopeptidase 2 Protein, CF | R&D Systems 3795-ZN-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Methionine Aminopeptidase 2 Protein, CF

catalog :

3795-ZN-020

quantity :

20 ug

price :

443 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Clauss Z, Wardzala C, Schlirf A, Wright N, Saini S, Onoa B, et al. Tunable, biodegradable grafting-from glycopolypeptide bottlebrush polymers. Nat Commun. 2021;12:6472 pubmed publisher
Węglarz Tomczak E, Talma M, Giurg M, Westerhoff H, Janowski R, Mucha A. Neutral metalloaminopeptidases APN and MetAP2 as newly discovered anticancer molecular targets of actinomycin D and its simple analogs. Oncotarget. 2018;9:29365-29378 pubmed publisher
Chiu J, Wong J, Hogg P. Redox regulation of methionine aminopeptidase 2 activity. J Biol Chem. 2014;289:15035-43 pubmed publisher

product information

master code :

3795-ZN

SKU :

3795-ZN-020

product name :

Recombinant Human Methionine Aminopeptidase 2 Protein, CF

unit size :

20 ug

description :

The Recombinant Human Methionine Aminopeptidase 2 Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Methionine Aminopeptidase 2 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Methionine Aminopeptidase 2/METAP2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

66 kDa, reducing conditions

theoretical molecular weight :

54 kDa

gene symbol :

METAP2

details of functionality :

Measure by its ability to remove methionine from a fluorogenic peptide substrate H-Met-Gly-Pro-AMC (Catalog # ES017 ). The resulting GP-AMC is cleaved by Recombinant Human DPPIV/CD26 (Catalog # 9168-SE ). The specific activity is 15 pmol/min/╡g, as measured using the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P50579

applications :

Enzyme Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived human Methionine Aminopeptidase 2/METAP2 protein Ala2-Tyr478, with a C-terminal 10-His tag

source short :

Sf 21 (baculovirus)

USD :

443 USD

alt names :

Amp2, eIF-2-associated p67 homolog, Initiation factor 2-associated 67 kDa glycoprotein, MAP 2, MAP2, MetAP 2, METAP2, methionine aminopeptidase 2, methionyl aminopeptidase 2, MNPEP, p67, p67EC 3.4.11.18, P67EIF2, Peptidase M 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage