product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Annexin A1 Protein, CF
catalog :
3770-AN-050
quantity :
50 ug
price :
499 USD
more info or order :
citations: 5
Reference
Zharkova O, Salamah M, Babak M, Rajan E, Lim L, Andrade F, et al. Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets. Int J Mol Sci. 2023;24: pubmed publisher
Alhasan H, Terkawi M, Matsumae G, Ebata T, Tian Y, Shimizu T, et al. Inhibitory role of Annexin A1 in pathological bone resorption and therapeutic implications in periprosthetic osteolysis. Nat Commun. 2022;13:3919 pubmed publisher
Zoued A, Zhang H, Zhang T, Giorgio R, Kuehl C, Fakoya B, et al. Proteomic analysis of the host-pathogen interface in experimental cholera. Nat Chem Biol. 2021;17:1199-1208 pubmed publisher
Rogers M, Buffolo F, Schlotter F, Atkins S, Lee L, Halu A, et al. Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis. Sci Adv. 2020;6: pubmed publisher
Maus R, Jakub J, Nevala W, Christensen T, Noble Orcutt K, Sachs Z, et al. Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation. Front Immunol. 2017;8:358 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3770-AN
SKU :
3770-AN-050
product name :
Recombinant Human Annexin A1 Protein, CF
Description :
The Recombinant Human Annexin A1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Annexin A1 Protein, CF has been validated for the following applications: Bioactivity.
target :
Annexin A1
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
38 kDa, reducing conditions
theoretical molecular weight :
39.4 kDa
gene symbol :
ANXA1
details of functionality :
Measured by its ability to inhibit proliferation of A549 human lung carcinoma cells. The ED50 for this effect is 1.0-4.0 µg/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P04083
applications :
Bioactivity
source :
E. coli-derived Recombinant Human Annexin A1 Protein
USD :
499 USD
alt names :
annexin A1, Annexin I, annexin I (lipocortin I), Annexin-1, ANX1, ANXA1, Calpactin II, calpactin-2, Chromobindin-9, Lipocortin I, LPC1, LPC1annexin-1, p35, Phospholipase A2 inhibitory protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.