product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human NRG1-beta 1/HRG1-beta 1 ECD Protein, CF
catalog :
377-HB-050/CF
quantity :
50 ug
price :
377 USD
more info or order :
citations: 14
Reference |
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Osada T, Hartman Z, Wei J, Lei G, Hobeika A, Gwin W, et al. Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancers. Breast Cancer Res. 2018;20:90 pubmed publisher
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Barkho B, Song H, Aimone J, Smrt R, Kuwabara T, Nakashima K, et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev. 2006;15:407-21 pubmed
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Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed
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Kastin A, Akerstrom V, Pan W. Neuregulin-1-beta1 enters brain and spinal cord by receptor-mediated transport. J Neurochem. 2004;88:965-70 pubmed
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image
image 1 :

Recombinant Human NRG1-beta 1/HRG1-beta 1 ECD Protein Bioactivity
product information
brand :
R&D Systems
master code :
377-HB/CF
SKU :
377-HB-050/CF
product name :
Recombinant Human NRG1-beta 1/HRG1-beta 1 ECD Protein, CF
unit size :
50 ug
description :
The Recombinant Human PSP94/MSMB Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PSP94/MSMB Protein, CF has been validated for the following applications: Binding Activity.
target :
Neuregulin-1 beta 1/NRG1 beta 1
category :
Proteins and Enzymes
alt names :
ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
all available conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
theoretical molecular weight :
26.9 kDa
gene symbol :
NRG1
details of functionality :
Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 2.5-12.5 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA58639
applications :
Bioactivity
source :
E. coli-derived Recombinant Human NRG1-beta 1/HRG1-beta 1 ECD Protein, CF
USD :
349
Jul-22 :
377 USD
sizes available :
50 ug
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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