product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Ephrin-A5 Fc Chimera Protein, CF
catalog :
374-EA-200
quantity :
200 ug
price :
313 USD
more info or order :
citations: 31
Reference |
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Sullivan C, Kümper M, Temple B, Maness P. The Neural Cell Adhesion Molecule (NCAM) Promotes Clustering and Activation of EphA3 Receptors in GABAergic Interneurons to Induce Ras Homolog Gene Family, Member A (RhoA)/Rho-associated protein kinase (ROCK)-mediated Growth Cone Collapse. J Biol Chem. 2016;291:26262-26272 pubmed
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Konstantinova I, Nikolova G, Ohara Imaizumi M, Meda P, Kucera T, Zarbalis K, et al. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell. 2007;129:359-70 pubmed
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Janes P, Saha N, Barton W, Kolev M, Wimmer Kleikamp S, Nievergall E, et al. Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell. 2005;123:291-304 pubmed
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Muñoz L, Zayachkivsky A, Kunz R, Hunt J, Wang G, Scott S. Ephrin-A5 inhibits growth of embryonic sensory neurons. Dev Biol. 2005;283:397-408 pubmed
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Sharfe N, Freywald A, Toro A, Dadi H, Roifman C. Ephrin stimulation modulates T cell chemotaxis. Eur J Immunol. 2002;32:3745-55 pubmed
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product information
brand :
R&D Systems
master code :
374-EA
SKU :
374-EA-200
product name :
Recombinant Human Ephrin-A5 Fc Chimera Protein, CF
unit size :
200 ug
description :
Endothelial lipase and lipoprotein lipase inhibitor
target :
Ephrin-A5
category :
Proteins and Enzymes
alt names :
AF1, AL-1, EFL-5, EFNA5, EPH-related receptor tyrosine kinase ligand 7, ephrin-A5, EphrinA5, EPLG7, GLC1M, LERK-7, LERK7EFL5, RAGS
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
all available conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
50-55 kDa, reducing conditions
theoretical molecular weight :
48.6 kDa (monomer)
gene symbol :
EFNA5
details of functionality :
Measured by its ability to compete with Biotinylated Recombinant Human Ephrin-A5 Fc Chimera (Catalog # BT374 ) for binding to immobilized recombinant mouse Eph-A3 Fc Chimera in a functional ELISA assay. Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P52803
applications :
Binding Activity
source :
NS0-derived Recombinant Human Ephrin-A5 Fc Chimera Protein, CF
USD :
289
Jul-22 :
313 USD
sizes available :
200 ug
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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