product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse SCGF/CLEC11a Protein, CF
catalog :
3729-SC-025/CF
quantity :
25 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Ramalingam P, Poulos M, Lazzari E, Gutkin M, Lopez D, Kloss C, et al. Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF. Nat Commun. 2020;11:666 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
3729-SC/CF
SKU :
3729-SC-025/CF
product name :
Recombinant Mouse SCGF/CLEC11a Protein, CF
description :
The Recombinant Mouse SCGF/CLEC11a Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse SCGF/CLEC11a Protein, CF has been validated for the following applications: Bioactivity.
target :
SCGF/CLEC11a
unit size :
25 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
50 kDa, reducing conditions
theoretical molecular weight :
35.1 kDa
gene symbol :
Clec11a
details of functionality :
Measured by its ability to promote the expansion of E16 rat liver mononuclear cells in vitro, in the presence of Recombinant Mouse SCF/c-kit Ligand (Catalog # 455-MC ), Recombinant Mouse Thrombopoietin/Tpo (Catalog # 488-TO ), and Recombinant Mouse Flt-3 Ligand (Catalog # 427-FL ). The ED50 for this effect is 0.1-0.4 µg/mL in the presence of cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody (Catalog # MAB050 ).
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
O88200
applications :
Bioactivity
product keywords :
3729-SC, rmSCGF-a, mSCGF-a, carrier-free, carrier free, 3729SC/CF, CLEC 11a, CLEC11 a
source :
NS0-derived Recombinant Mouse SCGF/CLEC11a Protein, CF
USD :
423
USD 2025 :
432 USD
alt names :
CLEC11a, CLECSF3, LSLCL, P47, SCGF
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.