Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein, CF | R&D Systems 3728-NG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein, CF

catalog :

3728-NG-050

quantity :

50 ug

price :

447 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Kawakami Y, Kurihara Y, Saito Y, Fujita Y, Yamashita T, Takei K. The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor. J Neurosci. 2018;38:2589-2604 pubmed publisher
Kurihara Y, Arie Y, Iketani M, Ito H, Nishiyama K, Sato Y, et al. The carboxyl-terminal region of Crtac1B/LOTUS acts as a functional domain in endogenous antagonism to Nogo receptor-1. Biochem Biophys Res Commun. 2012;418:390-5 pubmed publisher
Matsushita H, Endo S, Kobayashi E, Sakamoto Y, Kobayashi K, Kitaguchi K, et al. Differential but competitive binding of Nogo protein and class i major histocompatibility complex (MHCI) to the PIR-B ectodomain provides an inhibition of cells. J Biol Chem. 2011;286:25739-47 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3728-NG

SKU :

3728-NG-050

product name :

Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein, CF

Description :

The Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein, CF has been validated for the following applications: Bioactivity.

target :

Nogo-A

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

34.5 kDa (monomer)

gene symbol :

Rtn4

details of functionality :

Measured by its ability to inhibit neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Able to significantly inhibit neurite outgrowth when immobilized as a 3 µL droplet containing 200 ng on a nitrocellulose-coated microplate.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9JK11

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Rat Nogo-A Fc Chimera (aa 1026-1090) Protein

USD :

447 USD

alt names :

ASY;Nbla00271;Nbla10545;NI220/250;Nogo;NSP;NSP-CL;r;Reticulon-4;Rtn4;RTN4;RTN4-A;RTN4-B1;RTN4-B2;RTN4-C;RTN-X, NI220, NogoA, RTN4, RTN4A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage