product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Activin RIIB Fc Chimera Protein, CF
catalog :
3725-RB-050
quantity :
50 ug
price :
434 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Ohsawa Y, Hagiwara H, Nakatani M, Yasue A, Moriyama K, Murakami T, et al. Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition. J Clin Invest. 2006;116:2924-34 pubmed
Close J, Gumuscu B, Reh T. Retinal neurons regulate proliferation of postnatal progenitors and Müller glia in the rat retina via TGF beta signaling. Development. 2005;132:3015-26 pubmed
image
image 1 :
R&D Systems 3725-RB-050 image 1
Recombinant Mouse Activin RIIB Fc Chimera Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3725-RB
SKU :
3725-RB-050
product name :
Recombinant Mouse Activin RIIB Fc Chimera Protein, CF
Description :
The Recombinant Mouse Activin RIIB Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Activin RIIB Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Activin RIIB
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
61-63 kDa, reducing conditions
theoretical molecular weight :
40.5 kDa (monomer)
details of functionality :
Measured by its ability to inhibit Activin A-induced hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al . (1991) Method Enzymol. 198 :340. The ED50 for this effect is 5-30 ng/mL in the presence of 3 ng/mL of recombinant human Activin A.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P27040
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Activin RIIB Fc Chimera Protein
USD :
434 USD
alt names :
activin A receptor, type IIB, Activin receptor type IIB, activin receptor type-2B, ActivinRIIB, ActR-IIB, ACTRIIB, ACVR2B, EC 2.7.11, EC 2.7.11.30, MGC116908
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.