Recombinant Human RGM-C/Hemojuvelin Protein, CF | R&D Systems 3720-RG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human RGM-C/Hemojuvelin Protein, CF

catalog :

3720-RG-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Wu Q, Sun C, Lin H, Babitt J. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE. 2012;7:e46307 pubmed publisher
Krueger C, Hoffmann F. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE. 2010;5:e15511 pubmed publisher
Brasse Lagnel C, Poli M, Lesueur C, Grandchamp B, Lavoinne A, Beaumont C, et al. Immunoassay for human serum hemojuvelin. Haematologica. 2010;95:2031-7 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3720-RG

SKU :

3720-RG-050

product name :

Recombinant Human RGM-C/Hemojuvelin Protein, CF

Description :

The Recombinant Human RGM-C/Hemojuvelin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human RGM-C/Hemojuvelin Protein, CF has been validated for the following applications: Binding Activity.

target :

RGM-C/Hemojuvelin

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

50-55 kDa, 20 kDa and 32-37 kDa, reducing conditions

theoretical molecular weight :

40 kDa (mature), 14 kDa (N-terminus chain), 26 kDa (C-terminus chain)

gene symbol :

HFE2

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rhBMP-4 at 1 µg/mL can bind rhRGM-C with a linear range of 10-500 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q6ZVN8

applications :

Binding Activity

source :

NS0-derived Recombinant Human RGM-C/Hemojuvelin Protein

USD :

423 USD

alt names :

DL-M, haemojuvelin, hemochromatosis type 2 (juvenile), hemojuvelin, HFE2, HFE2AMGC23953, HJV, HJVHemochromatosis type 2 protein, JH, repulsive guidance molecule c, RGMC, RGMCRGM domain family member C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage