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product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein, CF
catalog :
3718-FB-010
quantity :
10 ug (also 25 ug, 100 ug, 1 mg)
price :
117 USD
citations: 21
Reference
Pokharel P, Newchurch A, Overby S, Spease C, Darzi L, Kraemer B. LM11a-31 Inhibits p75 Neurotrophin Receptor (p75 NTR ) Cleavage and is Neuroprotective in a Cell Culture Model of Parkinson's Disease. bioRxiv. 2024;: pubmed publisher
O Reilly M, Ho S, Coronel J, Zhu L, Liu W, Xue C, et al. linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability. Cell Rep. 2024;43:114240 pubmed publisher
Xue M, Dong L, Zhang H, Li Y, Qiu K, Zhao Z, et al. METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation. J Hematol Oncol. 2024;17:7 pubmed publisher
Prahallad A, Weiss A, Voshol H, Kerr G, Sprouffske K, Yuan T, et al. CRISPR Screening Identifies Mechanisms of Resistance to KRASG12C and SHP2 Inhibitor Combinations in Non-Small Cell Lung Cancer. Cancer Res. 2023;83:4130-4141 pubmed publisher
Chen Y, Chen Y, Li Q, Liu H, Han J, Zhang H, et al. Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells. Cell Rep. 2023;42:113308 pubmed publisher
Perez Estrada J, Tangeman J, Proto Newton M, Sanaka H, Smucker B, Del Rio Tsonis K. DISTINCT METABOLIC STATES DIRECT RETINAL PIGMENT EPITHELIUM CELL FATE DECISIONS. bioRxiv. 2023;: pubmed publisher
Wu M, Wang Z, Shi X, Zan D, Chen H, Yang S, et al. TGFβ1-RCN3-TGFBR1 loop facilitates pulmonary fibrosis by orchestrating fibroblast activation. Respir Res. 2023;24:222 pubmed publisher
De Martin A, Stanossek Y, L xfc tge M, Cadosch N, Onder L, Cheng H, et al. PI16+ reticular cells in human palatine tonsils govern T cell activity in distinct subepithelial niches. Nat Immunol. 2023;24:1138-1148 pubmed publisher
Zhang Q, Chen L, Huang L, Cheng H, Wang L, Xu L, et al. CD44 promotes angiogenesis in myocardial infarction through regulating plasma exosome uptake and further enhancing FGFR2 signaling transduction. Mol Med. 2022;28:145 pubmed publisher
Watts J, Grunseich C, Rodriguez Y, Liu Y, Li D, Burdick J, et al. A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE. Nucleic Acids Res. 2022;50:12497-12514 pubmed publisher
Raad S, David A, Sagniez M, Par xe9 B, Orfi Z, Dumont N, et al. iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage. Dis Model Mech. 2022;15: pubmed publisher
Tangeman J, P xe9 rez Estrada J, Van Zeeland E, Liu L, Danciutiu A, Grajales Esquivel E, et al. A Stage-Specific OTX2 Regulatory Network and Maturation-Associated Gene Programs Are Inherent Barriers to RPE Neural Competency. Front Cell Dev Biol. 2022;10:875155 pubmed publisher
Bonini F, Mosser S, Mor F, Boutabla A, Burch P, B xe9 duer A, et al. The Role of Interstitial Fluid Pressure in Cerebral Porous Biomaterial Integration. Brain Sci. 2022;12: pubmed publisher
Salokas K, Liu X, Ohman T, Chowdhury I, Gawriyski L, Keskitalo S, et al. Physical and functional interactome atlas of human receptor tyrosine kinases. EMBO Rep. 2022;23:e54041 pubmed publisher
Ting H, Yang H, Harn H, Chiu I, Su H, Li X, et al. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons. Cells. 2021;10: pubmed publisher
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product information
master code :
3718-FB
SKU :
3718-FB-010
product name :
Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein, CF
unit size :
10 ug (also 25 ug, 100 ug, 1 mg)
description :
The Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein, CF has been validated for the following applications: Bioactivity.
target :
FGF basic/FGF2/bFGF
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris-HCl and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
16 kDa
gene symbol :
FGF2
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 0.100-0.600 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human FGF basic/FGF2/bFGF (145 aa) Protein Bioactivity
accessionNumbers :
NP_001997
applications :
Bioactivity
source long :
E. coli -derived human FGF basic/FGF2/bFGF protein Ala144-Ser288
source short :
E. coli
USD :
117 USD
alt names :
Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.