Recombinant Human Active ZAP70 Protein, CF | R&D Systems 3709-KS-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Active ZAP70 Protein, CF

catalog :

3709-KS-010

quantity :

10 ug

price :

560 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Giardino Torchia M, Dutta D, Mittelstadt P, Guha J, Gaida M, Fish K, et al. Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome. Proc Natl Acad Sci U S A. 2018;115:2174-2179 pubmed publisher
Alam M, Gaida M, Debnath S, Tagad H, Miller Jenkins L, Appella E, et al. Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation. PLoS Biol. 2018;16:e2004111 pubmed publisher

image

image 1 :

Recombinant Human Active ZAP70 Protein SDS-PAGE

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3709-KS

SKU :

3709-KS-010

product name :

Recombinant Human Active ZAP70 Protein, CF

Description :

The Recombinant Human Active ZAP70 Protein, CF from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human Active ZAP70 Protein, CF has been validated for the following applications: Bioactivity.

target :

ZAP70

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM Glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% Glycerol.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.

species :

Human

observed molecular weight :

96 kDa

gene symbol :

ZAP70

details of functionality :

The specific activity of ZAP70 was determined to be 13 nmol/min/mg using a Poly (Glu:Tyr, 4:1) synthetic peptide substrate.

accessionNumbers :

NM_001079

applications :

Bioactivity

source :

Sf 9 (baculovirus)-derived Recombinant Human Active ZAP70 Protein

USD :

560 USD

alt names :

70 kDa zeta-associated protein, EC 2.7.10, EC 2.7.10.2, mrtle, mur, SRK, SRKFLJ17679, STD, STDFLJ17670, Syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, TZK, ZAP-70, zeta-chain (TCR) associated protein kinase (70 kD), zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, 70kD

storage :

This product is stable at Avoid repeated freeze-thaw cycles.

more info or order :

R&D Systems product webpage