product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Ephrin-A4 Fc Chimera Protein, CF
catalog :
369-EA-200
quantity :
200 ug
price :
341 USD
more info or order :
citations: 6
Reference
Chen Y, Yen Y, Jang C, Wang S, Huang H, Chen C, et al. Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. Sci Rep. 2021;11:644 pubmed publisher
Laing E, Navaratnarajah C, Cheliout Da Silva S, Petzing S, Xu Y, Sterling S, et al. Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 2019;116:20707-20715 pubmed publisher
Bäumer B, Kurz A, Borrie S, Sickinger S, Dours Zimmermann M, Zimmermann D, et al. Nogo receptor homolog NgR2 expressed in sensory DRG neurons controls epidermal innervation by interaction with Versican. J Neurosci. 2014;34:1633-46 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Hahn A, Kaufmann J, Wies E, Naschberger E, Panteleev Ivlev J, Schmidt K, et al. The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med. 2012;18:961-6 pubmed publisher
Dawson D, Hong J, Shen R, French S, Troke J, Wu Y, et al. Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene. 2007;26:4243-52 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
369-EA
SKU :
369-EA-200
product name :
Recombinant Human Ephrin-A4 Fc Chimera Protein, CF
Description :
The Recombinant Human Ephrin-A4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ephrin-A4 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Ephrin-A4
category :
Proteins and Enzymes
unit size :
200 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
50 kDa, reducing conditions
theoretical molecular weight :
43.7 kDa (monomer)
gene symbol :
EFNA4
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized rmEphA7/Fc Chimera at 2 µg/mL (100 µL/well) can bind rhEphrin-A4/Fc Chimera with a linear range of 0.16-10 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P52798
applications :
Binding Activity
source :
NS0-derived Recombinant Human Ephrin-A4 Fc Chimera Protein
USD :
341 USD
alt names :
EFL4, EFL-4, EFNA4, EPH-related receptor tyrosine kinase ligand 4, ephrin-A4, EphrinA4, EPLG4MGC125826, LERK-4, LERK4FLJ57652, ligand of eph-related kinase 4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.