Recombinant Human Ephrin-A4 Fc Chimera Protein, CF | R&D Systems 369-EA-200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Ephrin-A4 Fc Chimera Protein, CF

catalog :

369-EA-200

quantity :

200 ug

price :

359 USD

citations: 6

Reference
Chen Y, Yen Y, Jang C, Wang S, Huang H, Chen C, et al. Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells. Sci Rep. 2021;11:644 pubmed publisher
Laing E, Navaratnarajah C, Cheliout Da Silva S, Petzing S, Xu Y, Sterling S, et al. Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 2019;116:20707-20715 pubmed publisher
Bäumer B, Kurz A, Borrie S, Sickinger S, Dours Zimmermann M, Zimmermann D, et al. Nogo receptor homolog NgR2 expressed in sensory DRG neurons controls epidermal innervation by interaction with Versican. J Neurosci. 2014;34:1633-46 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Hahn A, Kaufmann J, Wies E, Naschberger E, Panteleev Ivlev J, Schmidt K, et al. The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus. Nat Med. 2012;18:961-6 pubmed publisher
Dawson D, Hong J, Shen R, French S, Troke J, Wu Y, et al. Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene. 2007;26:4243-52 pubmed

product information

master code :

369-EA

SKU :

369-EA-200

product name :

Recombinant Human Ephrin-A4 Fc Chimera Protein, CF

unit size :

200 ug

description :

The Recombinant Human Ephrin-A4 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Ephrin-A4 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Ephrin-A4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

50 kDa, reducing conditions

theoretical molecular weight :

43.7 kDa (monomer)

gene symbol :

EFNA4

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmEphA7/Fc Chimera at 2 ╡g/mL (100 ╡L/well) can bind rhEphrin-A4/Fc Chimera with a linear range of 0.16-10 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P52798

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Ephrin-A4 protein Human Ephrin-A4 (Leu26 - Gly171) Accession # P52798 IEGRMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

359 USD

alt names :

EFL4, EFL-4, EFNA4, EPH-related receptor tyrosine kinase ligand 4, ephrin-A4, EphrinA4, EPLG4MGC125826, LERK-4, LERK4FLJ57652, ligand of eph-related kinase 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.