This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Flt-3/Flk-2 Fc Chimera Protein
catalog :
368-ST
quantity :
50 ug
price :
349 USD
citations: 3
Reference
Kinney M, Vo L, Frame J, Barragan J, Conway A, Li S, et al. A systems biology pipeline identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019;37:810-818 pubmed publisher
Heshmati Y, Kharazi S, Türköz G, Chang D, Kamali Dolatabadi E, Boström J, et al. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation. Sci Rep. 2018;8:11202 pubmed publisher
Donahue R, Wersto R, Allay J, Agricola B, Metzger M, Nienhuis A, et al. High levels of lymphoid expression of enhanced green fluorescent protein in nonhuman primates transplanted with cytokine-mobilized peripheral blood CD34(+) cells. Blood. 2000;95:445-52 pubmed
product information
brand :
R&D Systems
master code :
368-ST
SKU :
368-ST-050
product name :
Recombinant Human Flt-3/Flk-2 Fc Chimera Protein
description :
The Recombinant Human Flt-3/Flk-2 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human Flt-3/Flk-2 Fc Chimera Protein has been validated for the following applications: Bioactivity.
target :
Flt-3/Flk-2/CD135
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
120 kDa, reducing conditions
theoretical molecular weight :
85.5 kDa (monomer)
gene symbol :
FLT3
details of functionality :
Measured by its ability to inhibit Flt-3 Ligand-induced proliferation of BaF3 mouse pro-B cells transfected with Flt-3. The ED50 for this effect is 0.01-0.03 µg/mL in the presence of rhFlt-3 Ligand at 2 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
368-ST
accessionNumbers :
AAA18947
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human Flt-3/Flk-2 protein Human Flt-3 (Asn27-Asn541) Accession # AAA18947 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
2020 USD :
349
2021 USD :
349 USD
alt names :
CD135, CD135 antigen, EC 2.7.10, fetal liver kinase 2, FL cytokine receptor, Flk-2, FLK2, Flt3, FLT-3, FLT3 receptor tyrosine kinase, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, STK-1, STK1EC 2.7.10.1, Tyrosine-protein kinase receptor FLT3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.