Recombinant Human Flt-3/Flk-2 Fc Chimera Protein | R&D Systems 368-ST-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Flt-3/Flk-2 Fc Chimera Protein

catalog :

368-ST-050

quantity :

50 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Tassou A, Thouaye M, Gilabert D, Jouvenel A, Leyris J, Sonrier C, et al. Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain. Prog Neurobiol. 2023;222:102405 pubmed publisher
Jiang Q, Isquith J, Ladel L, Mark A, Holm F, Mason C, et al. Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. Cell Rep. 2021;34:108670 pubmed publisher
Kinney M, Vo L, Frame J, Barragan J, Conway A, Li S, et al. A systems biology pipeline identifies regulatory networks for stem cell engineering. Nat Biotechnol. 2019;37:810-818 pubmed publisher
Heshmati Y, Kharazi S, Türköz G, Chang D, Kamali Dolatabadi E, Boström J, et al. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation. Sci Rep. 2018;8:11202 pubmed publisher
Donahue R, Wersto R, Allay J, Agricola B, Metzger M, Nienhuis A, et al. High levels of lymphoid expression of enhanced green fluorescent protein in nonhuman primates transplanted with cytokine-mobilized peripheral blood CD34(+) cells. Blood. 2000;95:445-52 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

368-ST

SKU :

368-ST-050

product name :

Recombinant Human Flt-3/Flk-2 Fc Chimera Protein

Description :

The Recombinant Human Flt-3/Flk-2 Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Human Flt-3/Flk-2 Fc Chimera Protein has been validated for the following applications: Bioactivity.

target :

Flt-3/Flk-2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

120 kDa, reducing conditions

theoretical molecular weight :

85.5 kDa (monomer)

gene symbol :

FLT3

details of functionality :

Measured by its ability to inhibit Flt-3 Ligand-induced proliferation of BaF3 mouse pro-B cells transfected with Flt-3. The ED50 for this effect is 0.01-0.03 µg/mL in the presence of rhFlt-3 Ligand at 2 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAA18947

applications :

Bioactivity

source :

NS0-derived Recombinant Human Flt-3/Flk-2 Fc Chimera Protein

USD :

434 USD

alt names :

CD135, CD135 antigen, EC 2.7.10, fetal liver kinase 2, FL cytokine receptor, Flk-2, FLK2, Flt3, FLT-3, FLT3 receptor tyrosine kinase, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, STK-1, STK1EC 2.7.10.1, Tyrosine-protein kinase receptor FLT3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage