Recombinant Human Complement Component C3a Protein, CF | R&D Systems 3677-C3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Complement Component C3a Protein, CF

catalog :

3677-C3

quantity :

25 ug

price :

359 USD

citations: 6

Reference
Fernandez Godino R, Pierce E. C3a triggers formation of sub-retinal pigment epithelium deposits via the ubiquitin proteasome pathway. Sci Rep. 2018;8:9679 pubmed publisher
Wang C, Cao S, Zhang D, Li H, Kijlstra A, Yang P. Increased Complement 3a Receptor is Associated with Behcet's disease and Vogt-Koyanagi-Harada disease. Sci Rep. 2017;7:15579 pubmed publisher
Samstad E, Niyonzima N, Nymo S, Aune M, Ryan L, Bakke S, et al. Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol. 2014;192:2837-45 pubmed publisher
Jensen B, Frandsen P, Raaby E, Schiøtz P, Skov P, Poulsen L. Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. J Leukoc Biol. 2014;95:893-901 pubmed publisher
Conroy A, Liles W, Molyneux M, Rogerson S, Kain K. Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi. PLoS ONE. 2011;6:e28540 pubmed publisher
Ruan B, Li X, Winkler A, Cunningham K, Kuai J, Greco R, et al. Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-? production in a receptor for advanced glycation end product-dependent manner. J Immunol. 2010;185:4213-22 pubmed publisher

product information

brand :

R&D Systems

master code :

3677-C3

SKU :

3677-C3-025

product name :

Recombinant Human Complement Component C3a Protein, CF

description :

The Recombinant Human Complement Component C3a Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Complement Component C3a Protein, CF has been validated for the following applications: Bioactivity.

target :

Complement Component C3a

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

theoretical molecular weight :

9.1 kDa

gene symbol :

details of functionality :

Measured by its ability to enhance IL-6 secretion by human peripheral blood mononuclear cells (PBMC). Fischer, W.H. et al . (1999) J. Immunol. 162 :453. The ED50 for this effect is 1.5-7.5 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

3677-C3

accessionNumbers :

NP_000055

applications :

Bioactivity

source :

E. coli -derived human Complement Component C3a protein Ser672-Arg748

2020 USD :

339

2021 USD :

359 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.