Recombinant Human Podoplanin Fc Chimera Protein, CF | R&D Systems 3670-PL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Podoplanin Fc Chimera Protein, CF

catalog :

3670-PL-050

quantity :

50 ug

price :

359 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Tseng C, Huang Y, Chang Y, Liao H, Chen Y, Hsieh P. Polysaccharide-containing fraction from Artemisia argyi inhibits tumor cell-induced platelet aggregation by blocking interaction of podoplanin with C-type lectin-like receptor 2. J Food Drug Anal. 2020;28:115-123 pubmed publisher
Muraguchi T, Nanba D, Nishimura E, Tashiro T. IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance. J Dermatol Sci. 2019;: pubmed publisher
Chang C, Chung C, Hsu C, Peng H, Huang T. Inhibitory effects of polypeptides derived from a snake venom C-type lectin, aggretin, on tumor cell-induced platelet aggregation. J Thromb Haemost. 2014;12:540-9 pubmed publisher
Bertozzi C, Schmaier A, Mericko P, Hess P, Zou Z, Chen M, et al. Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling. Blood. 2010;116:661-70 pubmed publisher

product information

brand :

R&D Systems

master code :

3670-PL

SKU :

3670-PL-050

product name :

Recombinant Human Podoplanin Fc Chimera Protein, CF

description :

The Podoplanin Fc Chimera Protein from 3670-PL-050 is derived from NS0-derived Recombinant Human Podoplanin Fc Chimera Protein. The Podoplanin Fc Chimera Protein has been validated for the following applications: NP_006465.

target :

Podoplanin

category :

Proteins and Enzymes

unit sizes :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

60-65 kDa, under reducing conditions

theoretical molecular weight :

37.1 kDa

gene symbol :

PDPN

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Podoplanin Fc Chimera (Catalog # 3670-PL ) can bind Recombinant Human CLEC-2 (Catalog # 1718-CL ) with an estimated Kd 4 nM.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_006465

applications :

Binding Activity

source :

NS0-derived Recombinant Human Podoplanin Fc Chimera Protein

USD :

359 USD

alt names :

36-KD, aggrus, Gp36, Gp38, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), OTS 8, OTS8, PA2.26 antigen, PDPN, podoplanin, RANDAM-2, T1A, T1A-2, T1-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage