product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human NGFR/TNFRSF16 Fc Chimera Protein, CF
catalog :
367-NR-050/CF
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 8
Reference
Suzuki A, Matsuura D, Kanatani H, Yano S, Tsunakawa M, Matsuyama S, et al. Inhibitory Effects of Polyacetylene Compounds from Panax ginseng on Neurotrophin Receptor-Mediated Hair Growth. Biol Pharm Bull. 2017;40:1784-1788 pubmed publisher
Jia R, Shepheard S, Jin J, Hu F, Zhao X, Xue L, et al. Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort. Sci Rep. 2017;7:5127 pubmed publisher
Shepheard S, Wuu J, Cardoso M, Wiklendt L, Dinning P, Chataway T, et al. Urinary p75ECD: A prognostic, disease progression, and pharmacodynamic biomarker in ALS. Neurology. 2017;88:1137-1143 pubmed publisher
Adams R, Burnley R, Valenzano C, Qureshi O, Doyle C, Lumb S, et al. Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling. Sci Rep. 2017;7:37716 pubmed publisher
Shepheard S, Chataway T, Schultz D, Rush R, Rogers M. The extracellular domain of neurotrophin receptor p75 as a candidate biomarker for amyotrophic lateral sclerosis. PLoS ONE. 2014;9:e87398 pubmed publisher
Fobian K, Owczarek S, Budtz C, Bock E, Berezin V, Pedersen M. Peptides derived from the solvent-exposed loops 3 and 4 of BDNF bind TrkB and p75(NTR) receptors and stimulate neurite outgrowth and survival. J Neurosci Res. 2010;88:1170-81 pubmed publisher
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher
Song X, Zhong J, Wang X, Zhou X. Suppression of p75NTR does not promote regeneration of injured spinal cord in mice. J Neurosci. 2004;24:542-6 pubmed
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
367-NR/CF
SKU :
367-NR-050/CF
product name :
Recombinant Human NGFR/TNFRSF16 Fc Chimera Protein, CF
description :
The Recombinant Human NGFR/TNFRSF16 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human NGFR/TNFRSF16 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
NGFR/TNFRSF16
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
70-80 kDa, reducing conditions
theoretical molecular weight :
51 kDa (monomer)
gene symbol :
NGFR
details of functionality :
Measured by its ability to inhibit ß-NGF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.2-0.6 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P08138
applications :
Bioactivity
product keywords :
367-NR, rhNGF R/p75 NTR/Fc, hNGF R, carrier-free, carrier free, 367NR/CF, NGF R, TNFRSF 16, NGF Receptor, p75NTR, p75 NT R, p75LNGFR, p75(Ntr), Nerve Growth Factor Receptor, cytokine, cytokines
source :
Sf 21 (baculovirus)-derived Recombinant Human NGFR/TNFRSF16 Fc Chimera Protein, CF
USD :
423
USD 2025 :
432 USD
alt names :
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF R, NGF receptor, p75 ICD, p75 NTR, TNFRSF16, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.