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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CCL21/6Ckine Protein
catalog :
366-6C-025
quantity :
25 ug
price :
377 USD
more info or order :
citations: 30
Reference
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Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanárová O, Radaszkiewicz K, Pícková M, et al. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. elife. 2021;10: pubmed publisher
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Dhandapani H, Jayakumar H, Seetharaman A, Singh S, Ganeshrajah S, Jagadish N, et al. Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4+, CD8+ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer. Cancer Cell Int. 2021;21:473 pubmed publisher
Capitano M, Jaiswal A, Broxmeyer H, Pride Y, Glover S, Amlashi F, et al. A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease. PLoS ONE. 2021;16:e0252805 pubmed publisher
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Cantero Pérez J, Grau Expósito J, Serra Peinado C, Rosero D, Luque Ballesteros L, Astorga Gamaza A, et al. Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa. Nat Commun. 2019;10:4739 pubmed publisher
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Caielli S, Veiga D, Balasubramanian P, Athale S, Domic B, Murat E, et al. A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate. Nat Med. 2019;25:75-81 pubmed publisher
Mohamed S, Jantan I, Nafiah M, Seyed M, Chan K. Dendritic cells pulsed with generated tumor cell lysate from Phyllanthus amarus Schum. & Thonn. induces anti-tumor immune response. BMC Complement Altern Med. 2018;18:232 pubmed publisher
Kobayashi D, Endo M, Ochi H, Hojo H, Miyasaka M, Hayasaka H. Regulation of CCR7-dependent cell migration through CCR7 homodimer formation. Sci Rep. 2017;7:8536 pubmed publisher
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Swaims Kohlmeier A, Haaland R, Haddad L, Sheth A, Evans Strickfaden T, Lupo L, et al. Progesterone Levels Associate with a Novel Population of CCR5+CD38+ CD4 T Cells Resident in the Genital Mucosa with Lymphoid Trafficking Potential. J Immunol. 2016;197:368-76 pubmed publisher
Yu Q, Lou X, He Y. Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathway. PLoS ONE. 2015;10:e0120855 pubmed publisher
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product information
brand :
R&D Systems
master code :
366-6C
SKU :
366-6C-025
product name :
Recombinant Human CCL21/6Ckine Protein
description :
The Recombinant Human CCL21/6Ckine Protein from R&D Systems is derived from E. coli.
target :
CCL21/6Ckine
category :
Proteins and Enzymes
sizes available :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
16-17 kDa, reducing conditions
theoretical molecular weight :
12 kDa
gene symbol :
CCL21
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR7. The ED50 for this effect is 3-15 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q6ICR7
source :
E. coli-derived Recombinant Human CCL21/6Ckine Protein
USD :
377
USD 2023 :
377 USD
alt names :
6Ckine, 6CkineSmall-inducible cytokine A21, Beta-chemokine exodus-2, chemokine (C-C motif) ligand 21, CKb9, exodus-2, member 21, SCYA21, SCYA21MGC34555, secondary lymphoid tissue chemokine, SLC, SLCSecondary lymphoid-tissue chemokine, TCA-4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.