Recombinant Human CCL17/TARC Protein | R&D Systems 364-DN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL17/TARC Protein

catalog :

364-DN

quantity :

25 ug

price :

299 USD

citations: 15

Reference
Nakagawa M, Schmitz R, Xiao W, Goldman C, Xu W, Yang Y, et al. Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma. J Exp Med. 2014;211:2497-505 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Paantjens A, van de Graaf E, Kwakkel van Erp J, Hoefnagel T, van Kessel D, van den Bosch J, et al. Lung transplantation affects expression of the chemokine receptor type 4 on specific T cell subsets. Clin Exp Immunol. 2011;166:103-9 pubmed publisher
Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
Baatar D, Olkhanud P, Newton D, Sumitomo K, Biragyn A. CCR4-expressing T cell tumors can be specifically controlled via delivery of toxins to chemokine receptors. J Immunol. 2007;179:1996-2004 pubmed
Heijink I, Marcel Kies P, van Oosterhout A, Postma D, Kauffman H, Vellenga E. Der p, IL-4, and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium. Am J Respir Cell Mol Biol. 2007;36:351-9 pubmed
Hirahara K, Liu L, Clark R, Yamanaka K, Fuhlbrigge R, Kupper T. The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors. J Immunol. 2006;177:4488-94 pubmed
Nakayama T, Shirane J, Hieshima K, Shibano M, Watanabe M, Jin Z, et al. Novel antiviral activity of chemokines. Virology. 2006;350:484-92 pubmed
Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M. TARC augments TNF-alpha-induced CTACK production in keratinocytes. Exp Dermatol. 2004;13:551-7 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
Liu L, Jarjour N, Busse W, Kelly E. Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med. 2004;169:1118-24 pubmed
Banisadr G, Queraud Lesaux F, Boutterin M, Pelaprat D, Zalc B, Rostene W, et al. Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain. J Neurochem. 2002;81:257-69 pubmed
Thompson S, Luyrink L, Graham T, Tsoras M, Ryan M, Passo M, et al. Chemokine receptor CCR4 on CD4+ T cells in juvenile rheumatoid arthritis synovial fluid defines a subset of cells with increased IL-4:IFN-gamma mRNA ratios. J Immunol. 2001;166:6899-906 pubmed

product information

brand :

R&D Systems

master code :

364-DN

SKU :

364-DN-025

product name :

Recombinant Human CCL17/TARC Protein

description :

The Recombinant Human CCL17/TARC Protein from R&D Systems is derived from E. coli.

target :

CCL17/TARC

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

8 kDa

gene symbol :

CCL17

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR4. The ED50 for this effect is 2-6 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

364-DN

accessionNumbers :

Q92583.1

source :

E. coli -derived human CCL17/TARC protein Ala24-Ser94

2020 USD :

299

2021 USD :

299 USD

alt names :

ABCD-2, CC chemokine TARC, C-C motif chemokine 17, chemokine (C-C motif) ligand 17, MGC138273, SCYA17, SCYA17MGC138271, small inducible cytokine subfamily A (Cys-Cys), member 17, Small-inducible cytokine A17, T cell-directed CC chemokine, TARC, TARCA-152E5.3, Thymus and activation-regulated chemokine

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.