Recombinant Human RGM-B Protein, CF | R&D Systems 3630-RG-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human RGM-B Protein, CF

catalog :

3630-RG-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco L, et al. RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance. J Exp Med. 2014;211:943-59 pubmed publisher
Wu Q, Sun C, Lin H, Babitt J. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs). PLoS ONE. 2012;7:e46307 pubmed publisher

product information

brand :

R&D Systems

master code :

3630-RG

SKU :

3630-RG-050

product name :

Recombinant Human RGM-B Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human RGM-B Protein, CF from R&D Systems is derived from NS0. The Recombinant Human RGM-B Protein, CF has been validated for the following applications: Binding Activity.

target :

RGM-B

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

20 kDa and 35 kDa, reducing conditions

theoretical molecular weight :

13.4 kDa (N-terminus chain), 27.7 kDa (C-terminus chain)

gene symbol :

RGMB

details of functionality :

Measured by its binding ability in a functional ELISA. Immoblized rhBMP-4 at 1 ╡g/mL (100 ╡L/well) can bind rhRGM-B with a linear range of 10-500 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAH67736

applications :

Binding Activity

source :

NS0-derived Recombinant Human RGM-B Protein, CF

USD :

456 USD

alt names :

DKFZp434P228, Dragon, DRG11-responsive axonal guidance and outgrowth of neurite, RGM domain family, member B, RGMB

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage