product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse RGM-B Protein, CF
catalog :
3597-RG-050
quantity :
50 ug
price :
468 USD
more info or order :
citations: 3
Reference
Nie X, Chen W, Zhu Y, Huang B, Yu W, Wu Z, et al. B7-DC (PD-L2) costimulation of CD4+ T-helper 1 response via RGMb. Cell Mol Immunol. 2018;15:888-897 pubmed publisher
Xiao Y, Yu S, Zhu B, Bedoret D, Bu X, Francisco L, et al. RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance. J Exp Med. 2014;211:943-59 pubmed publisher
Liu X, Hashimoto M, Horii H, Yamaguchi A, Naito K, Yamashita T. Repulsive guidance molecule b inhibits neurite growth and is increased after spinal cord injury. Biochem Biophys Res Commun. 2009;382:795-800 pubmed publisher
product information
brand :
R&D Systems
master code :
3597-RG
SKU :
3597-RG-050
product name :
Recombinant Mouse RGM-B Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse RGM-B Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse RGM-B Protein, CF has been validated for the following applications: Binding Activity.
target :
RGM-B
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
20 kDa and 27 kDa, reducing conditions
theoretical molecular weight :
13.3 kDa (N-terminus chain), 27.8 kDa (C-terminus chain)
gene symbol :
Rgmb
details of functionality :
Measured by its binding ability in a functional ELISA. Immoblized rhBMP-4 at 1 ╡g/mL (100 ╡L/well) can bind rmRGM-B with a linear range of 0.016-1á╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q7TQ33
applications :
Binding Activity
source :
NS0-derived Recombinant Mouse RGM-B Protein, CF
USD :
468 USD
alt names :
DKFZp434P228, Dragon, DRG11-responsive axonal guidance and outgrowth of neurite, RGM domain family, member B, RGMB
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.