product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Relaxin-2 (B-33/A-24) Protein, CF
catalog :
3596-RN-025/CF
quantity :
25 ug
price :
432 USD
more info or order :
citations: 4
Reference
Sun J, Hao W, Fillmore N, Ma H, Springer D, Yu Z, et al. Human Relaxin-2 Fusion Protein Treatment Prevents and Reverses Isoproterenol-Induced Hypertrophy and Fibrosis in Mouse Heart. J Am Heart Assoc. 2019;8:e013465 pubmed publisher
Kamimoto H, Kobayashi Y, Moriyama K. Relaxin 2 carried by magnetically directed liposomes accelerates rat midpalatal suture expansion and subsequent new bone formation. Bone Rep. 2019;10:100202 pubmed publisher
Lee K, Hsieh Y, Chan C, Sun H, Huang Y, Hou M, et al. Human relaxin-2 attenuates hepatic steatosis and fibrosis in mice with non-alcoholic fatty liver disease. Lab Invest. 2019;: pubmed publisher
Krueger C, Hoffmann F. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE. 2010;5:e15511 pubmed publisher
product information
brand :
R&D Systems
master code :
3596-RN/CF
SKU :
3596-RN-025/CF
product name :
Recombinant Human Relaxin-2 (B-33/A-24) Protein, CF
unit size :
25 ug
seo description :
The Recombinant Human Relaxin-2 (B-33/A-24) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Relaxin-2 (B-33/A-24) Protein, CF has been validated for the following applications: Bioactivity.
target :
Relaxin-2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
theoretical molecular weight :
2.7 kDa (A chain), 3.9 kDa (B chain)
gene symbol :
RLN2
details of functionality :
Measured by its ability to induce cAMP accumulation in THP-1 human acute monocytic leukemia cells. Parsell, D.A. et al . (1996) J. Biol. Chem. 271 :27936. The ED50 for this effect is 0.5-2.5 ng/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P04090
applications :
Bioactivity
source :
E. coli-derived Recombinant Human Relaxin-2 (B-33/A-24) Protein, CF
extended description :
Replaces 2804-RN/CF
USD :
432 USD
product details :
Replaces 2804-RN/CF
alt names :
bA12D24.1.1, bA12D24.1.2, H2, relaxin 2, Relaxin2, RLN2, RLXH2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.