Recombinant Human CD74 Protein, CF | R&D Systems 3590-CD-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD74 Protein, CF

catalog :

3590-CD-050

quantity :

50 ug

price :

432 USD

citations: 2

Reference
Li X, Abrahams C, Yu A, Embry M, Henningsen R, Dealmeida V, et al. Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001. Oncotarget. 2023;14:1-13 pubmed publisher
Zhao S, Molina A, Yu A, Hanson J, Cheung H, Li X, et al. High frequency of CD74 expression in lymphomas: implications for targeted therapy using a novel anti-CD74-drug conjugate. J Pathol Clin Res. 2019;5:12-24 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

3590-CD

SKU :

3590-CD-050

product name :

Recombinant Human CD74 Protein, CF

description :

The Recombinant Human CD74 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human CD74 Protein, CF has been validated for the following applications: Bioactivity.

target :

CD74

unit size :

50 ug

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

30-35 kDa, reducing conditions

theoretical molecular weight :

19.3 kDa

gene symbol :

CD74

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of HeLa human cervical epithelial carcinoma cells. When 5 x 104 cells per well are added to Recombinant Human CD74 coated plates, cell adhesion is enhanced in a dose dependent manner. The ED50 for this effect is 0.6-3 µg/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_004346

applications :

Bioactivity

product keywords :

3590-CD, rhCD74, hCD74, carrier-free, carrier free, 359O-CD, 3590CD, Iag, HLA-DR-GAMMA, MHC class II, gastric epithelial cells, Ia-Associated Invariant Chain, meningeal lymphatic vessels, HLA Class II Histocompatibility Antigen Gamma Chain, P04233

source :

CHO-derived Recombinant Human CD74 Protein, CF

USD :

423

USD 2025 :

432 USD

alt names :

CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, CLIP, DHLAG, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, INVG34, MHC HLA-DR gamma chain, p33