product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human HVEM/TNFRSF14 Fc Chimera Protein, CF
catalog :
356-HV-100/CF
quantity :
100 ug
price :
425 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Boice M, Salloum D, Mourcin F, Sanghvi V, Amin R, Oricchio E, et al. Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells. Cell. 2016;167:405-418.e13 pubmed publisher
El Far M, Pellerin C, Pilote L, Fortin J, Lessard I, Peretz Y, et al. CD160 isoforms and regulation of CD4 and CD8 T-cell responses. J Transl Med. 2014;12:217 pubmed publisher
Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, et al. Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy. Biomaterials. 2010;31:3357-63 pubmed publisher
product information
brand :
R&D Systems
master code :
356-HV/CF
SKU :
356-HV-100/CF
product name :
Recombinant Human HVEM/TNFRSF14 Fc Chimera Protein, CF
unit size :
100 ug
seo description :
The Recombinant Human HVEM/TNFRSF14 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human HVEM/TNFRSF14 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
HVEM/TNFRSF14
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
60 kDa, reducing conditions
theoretical molecular weight :
45 kDa (monomer)
gene symbol :
TNFRSF14
details of functionality :
Measured by its ability to inhibit TNF┐▀-mediated cytotoxicity using L-929 mouse fibroblast cells. The ED50 for this effect is 2.5-10 ╡g/mL in the presence of 50 pg/mL of Recombinant Human TNF┐▀/TNFSF1 (Catalog # 211-TB ).
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q92956.3
applications :
Bioactivity
source :
NS0-derived Recombinant Human HVEM/TNFRSF14 Fc Chimera Protein, CF
extended description :
His-tag
USD :
425 USD
product details :
His-tag
alt names :
ATAR, CD270, CD270 antigen, CD40-like protein, Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, HVEMTR2HVEAATAR, LIGHTR, TNFRSF14, tumor necrosis factor receptor superfamily member 14, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entrymediator), Tumor necrosis factor receptor-like 2, tumor necrosis factor receptor-like gene2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.