This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Chitotriosidase/CHIT1 Protein, CF
catalog :
3559-GH
quantity :
10 ug
price :
309 USD
citations: 3
Reference
Hsu M, Rayasam A, Kijak J, Choi Y, Harding J, Marcus S, et al. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nat Commun. 2019;10:229 pubmed publisher
Starossom S, Campo Garcia J, Woelfle T, Romero Suarez S, Olah M, Watanabe F, et al. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019;10:217 pubmed publisher
Agapov E, Battaile J, Tidwell R, Hachem R, Patterson G, Pierce R, et al. Macrophage chitinase 1 stratifies chronic obstructive lung disease. Am J Respir Cell Mol Biol. 2009;41:379-84 pubmed publisher
product information
brand :
R&D Systems
master code :
3559-GH
SKU :
3559-GH-010
product name :
Recombinant Human Chitotriosidase/CHIT1 Protein, CF
description :
The Recombinant Human Chitotriosidase/CHIT1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Chitotriosidase/CHIT1 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Chitotriosidase/CHIT1
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in Tris and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
52 kDa, reducing conditions
theoretical molecular weight :
51 kDa
gene symbol :
CHIT1
details of functionality :
Measured by its ability to cleave 4-Methylumbelliferyl-beta-D-N,N’,N”-triacetylchitotriose (4-MU-TACT). The specific activity is 1,500 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
3559-GH
accessionNumbers :
NP_003456
applications :
Enzyme Activity
source :
Mouse myeloma cell line, NS0-derived human Chitotriosidase/CHIT1 protein Ala22-Asn466, with a C-terminal 10-His tag
2020 USD :
309
2021 USD :
309 USD
alt names :
CHI3, CHIT1, CHITCHI3, chitinase 1 (chitotriosidase), Chitinase-1, chitotriosidase-1, EC 3.2.1.14, FLJ00314, MGC125322, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.