product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human/Mouse/Rat BMP-2 (E. coli-expressed)
catalog :
355-BEC-010
quantity :
10 ug
price :
252 USD
more info or order :
R&D Systems product webpage
citations: 10
Reference
Kajander K, Sirki xe4 S, Vallittu P, Heino T, M xe4 xe4 tt xe4 J. Bioactive glasses promote rapid pre-osteoblastic cell migration in contrast to hydroxyapatite, while carbonated apatite shows migration inhibiting properties. Sci Rep. 2023;13:20587 pubmed publisher
Nonoyama S, Karakida T, Chiba Ohkuma R, Yamamoto R, Ujiie Y, Nagano T, et al. Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells. Cells. 2021;10: pubmed publisher
Kinoshita M, Yamada A, Sasa K, Ikezaki K, Shirota T, Kamijo R. Phorbol-12-myristate 13-acetate inhibits Nephronectin gene expression via Protein kinase C alpha and c-Jun/c-Fos transcription factors. Sci Rep. 2021;11:20360 pubmed publisher
Hidaka Y, Chiba Ohkuma R, Karakida T, Onuma K, Yamamoto R, Fujii Abe K, et al. Combined Effect of Midazolam and Bone Morphogenetic Protein-2 for Differentiation Induction from C2C12 Myoblast Cells to Osteoblasts. Pharmaceutics. 2020;12: pubmed publisher
Nguyen Yamamoto L, Tanaka K, St Arnaud R, Goltzman D. Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification. JCI Insight. 2019;4: pubmed publisher
Mouillesseaux K, Wiley D, Saunders L, Wylie L, Kushner E, Chong D, et al. Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. Nat Commun. 2016;7:13247 pubmed publisher
Baas R, Sijm A, van Teeffelen H, van Es R, Vos H, Marc Timmers H. Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin. J Biol Chem. 2016;291:24121-24132 pubmed
Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, et al. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury. Stem Cells Transl Med. 2014;3:334-45 pubmed publisher
Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher
Lin L, Valore E, Nemeth E, Goodnough J, Gabayan V, Ganz T. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 2007;110:2182-9 pubmed
product information
master code :
355-BEC
SKU :
355-BEC-010
product name :
Recombinant Human/Mouse/Rat BMP-2 (E. coli-expressed)
unit size :
10 ug
description :
The Recombinant Human/Mouse/Rat BMP-2 (E. coli-expressed) from R&D Systems is derived from E. coli. The Recombinant Human/Mouse/Rat BMP-2 (E. coli-expressed) has been validated for the following applications: Bioactivity.
target :
BMP-2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human, Mouse, Rat
theoretical molecular weight :
12.8 kDa (monomer)
gene symbol :
BMP2
details of functionality :
Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.08-0.48 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human/Mouse/Rat BMP-2 (E. coli-expressed) Bioactivity
accessionNumbers :
P12643
applications :
Bioactivity
source long :
E. coli -derived BMP-2 protein Ala284-Arg396 This form is not detected using human BMP-2 Quantikine ELISA (Catalog # DBP200 ).
source short :
E. coli
USD :
252 USD
alt names :
BDA2, BMP2, BMP-2, BMP-2A, BMP2ABone morphogenetic protein 2A, bone morphogenetic protein 2, SSFSC
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.