This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Periostin/OSF-2 Protein, CF
catalog :
3548-F2-050
quantity :
50 ug
price :
432 USD
citations: 31
Reference
Jin X, Deng Q, Ye S, Liu S, Fu Y, Liu Y, et al. Cancer-associated fibroblast-derived periostin promotes papillary thyroid tumor growth through integrin-FAK-STAT3 signaling. Theranostics. 2024;14:3014-3028 pubmed publisher
Liu B, Wu T, Lin B, Liu X, Liu Y, Song G, et al. Periostin-TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer. Br J Cancer. 2024;130:358-368 pubmed publisher
Hirata R, Iwata T, Fujita T, Nagahara T, Matsuda S, Sasaki S, et al. Periostin regulates integrin expression in gingival epithelial cells. J Oral Biosci. 2024;66:170-178 pubmed publisher
Suzuki M, Ototake Y, Akita A, Asami M, Ikeda N, Watanabe T, et al. Periostin-An inducer of pro-fibrotic phenotype in monocytes and monocyte-derived macrophages in systemic sclerosis. PLoS ONE. 2023;18:e0281881 pubmed publisher
Pang L, Dunterman M, Xuan W, Gonzalez A, Lin Y, Hsu W, et al. Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma. Cell Rep. 2023;42:112127 pubmed publisher
Alesutan I, Henze L, Boehme B, Luong T, Zickler D, Pieske B, et al. Periostin Augments Vascular Smooth Muscle Cell Calcification via β-Catenin Signaling. Biomolecules. 2022;12: pubmed publisher
Martín Alonso M, Iqbal S, Vornewald P, Lindholm H, Damen M, Martinez F, et al. Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage. Nat Commun. 2021;12:6741 pubmed publisher
Yamato H, Kimura K, Fukui E, Kanou T, Ose N, Funaki S, et al. Periostin secreted by activated fibroblasts in idiopathic pulmonary fibrosis promotes tumorigenesis of non-small cell lung cancer. Sci Rep. 2021;11:21114 pubmed publisher
Jamal Jameel K, Gallert W, Yanik S, Panek S, Kronsbein J, Jungck D, et al. Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD. Int J Mol Sci. 2021;22: pubmed publisher
Ikeda Iwabu Y, Taniyama Y, Katsuragi N, Sanada F, Koibuchi N, Shibata K, et al. Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis. Cells. 2021;10: pubmed publisher
Yoshihara T, Nanri Y, Nunomura S, Yamaguchi Y, Feghali Bostwick C, Ajito K, et al. Periostin plays a critical role in the cell cycle in lung fibroblasts. Respir Res. 2020;21:38 pubmed publisher
Ma H, Wang J, Zhao X, Wu T, Huang Z, Chen D, et al. Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation. Cell Rep. 2020;30:793-806.e6 pubmed publisher
Ono J, Takai M, Kamei A, Nunomura S, Nanri Y, Yoshihara T, et al. Periostin forms a functional complex with IgA in human serum. Allergol Int. 2020;69:111-120 pubmed publisher
Kim S, Nikoloudaki G, Michelsons S, Creber K, Hamilton D. Fibronectin synthesis, but not α-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling. Sci Rep. 2019;9:2708 pubmed publisher
Ma Z, Zhao X, Deng M, Huang Z, Wang J, Wu Y, et al. Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells. Cell Rep. 2019;26:1533-1543.e4 pubmed publisher
Barretto K, Swanson C, Nguyen C, Annis D, Esnault S, Mosher D, et al. Control of cytokine-driven eosinophil migratory behavior by TGF-beta-induced protein (TGFBI) and periostin. PLoS ONE. 2018;13:e0201320 pubmed publisher
Yu K, Yao C, Jeng J, Shieh H, Chen Y. Periostin inhibits mechanical stretch-induced apoptosis in osteoblast-like MG-63 cells. J Formos Med Assoc. 2018;117:292-300 pubmed publisher
Mineshige T, Kamiie J, Sugahara G, Shirota K. A study on periostin involvement in the pathophysiology of canine atopic skin. J Vet Med Sci. 2017;: pubmed publisher
Kim B, Kwon Y, Park G, Choi E, Seo J, Jang I, et al. Identification of a novel angiogenic peptide from periostin. PLoS ONE. 2017;12:e0187464 pubmed publisher
Zhang R, Yao R, Li J, Dong G, Ma M, Zheng Q, et al. Activated hepatic stellate cells secrete periostin to induce stem cell-like phenotype of residual hepatocellular carcinoma cells after heat treatment. Sci Rep. 2017;7:2164 pubmed publisher
Johansson M, Khanna M, Bortnov V, Annis D, Nguyen C, Mosher D. IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration. Clin Exp Allergy. 2017;47:1263-1274 pubmed publisher
Nakama T, Yoshida S, Ishikawa K, Kubo Y, Kobayashi Y, Zhou Y, et al. Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal Neovascularization. Mol Ther Nucleic Acids. 2017;6:279-289 pubmed publisher
Zhang F, Luo K, Rong Z, Wang Z, Luo F, Zhang Z, et al. Periostin Upregulates Wnt/β-Catenin Signaling to Promote the Osteogenesis of CTLA4-Modified Human Bone Marrow-Mesenchymal Stem Cells. Sci Rep. 2017;7:41634 pubmed publisher
Pita Thomas W, Barroso García G, Moral V, Hackett A, Cavalli V, Nieto Diaz M. Identification of axon growth promoters in the secretome of the deer antler velvet. Neuroscience. 2017;340:333-344 pubmed publisher
Park S, Piao Y, Jeong K, Dong J, de Groot J. Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models. Mol Cancer Ther. 2016;15:2187-97 pubmed publisher
Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, et al. Periostin Is a Key Niche Component for Wound Metastasis of Melanoma. PLoS ONE. 2015;10:e0129704 pubmed publisher
Ryner L, Guan Y, Firestein R, Xiao Y, Choi Y, Rabe C, et al. Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer. Clin Cancer Res. 2015;21:2941-51 pubmed publisher
Zhou W, Ke S, Huang Z, Flavahan W, Fang X, Paul J, et al. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nat Cell Biol. 2015;17:170-82 pubmed publisher
Mael Ainin M, Abed A, Conway S, Dussaule J, Chatziantoniou C. Inhibition of periostin expression protects against the development of renal inflammation and fibrosis. J Am Soc Nephrol. 2014;25:1724-36 pubmed publisher
Lee Y, Kim I, Park S, Kim Y, Lee J, Noh D, et al. Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis. Mol Ther. 2013;21:1004-13 pubmed publisher
Ben Q, Zhao Z, Ge S, Zhou J, Yuan F, Yuan Y. Circulating levels of periostin may help identify patients with more aggressive colorectal cancer. Int J Oncol. 2009;34:821-8 pubmed
product information
master code :
3548-F2
SKU :
3548-F2-050
product name :
Recombinant Human Periostin/OSF-2 Protein, CF
unit size :
50 ug
description :
The Recombinant Human Periostin/OSF-2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Periostin/OSF-2 Protein, CF has been validated for the following applications: Bioactivity.
target :
Periostin/OSF-2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
85-90 kDa, reducing conditions
theoretical molecular weight :
91.7 kDa
gene symbol :
POSTN
details of functionality :
Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. Immobilized Recombinant Human Periostin/OSF-2 at 10 ╡g/mL (100 ╡L/well) induces 50% cell adhesion.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q15063
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human Periostin/OSF-2 protein Asn22-Gln836, with a C-terminal 6-His tag
source short :
NS0
USD :
432 USD
alt names :
Fasciclin I-like, MGC119510, MGC119511, OSF2, OSF-2, OSF-2osteoblast specific factor 2 (fasciclin I-like), OSF2periodontal ligament-specific periostin, Osteoblast-specific factor 2, PDLPOSTN, periostin, periostin isoform thy2, periostin isoform thy4, periostin isoform thy6, periostin isoform thy8, periostin, osteoblast specific factor, PNRP11-412K4.1, POSTN, TRIF52
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.