product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human VEGFR1/Flt-1 (aa 27-328) Fc Chimera, CF
catalog :
3516-FL-050
quantity :
50 ug
price :
458 USD
more info or order :
citations: 1
Reference
Miyake T, Kumasawa K, Sato N, Takiuchi T, Nakamura H, Kimura T. Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells. Sci Rep. 2016;6:24853 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
3516-FL
SKU :
3516-FL-050
product name :
Recombinant Human VEGFR1/Flt-1 (aa 27-328) Fc Chimera, CF
Description :
The Recombinant Human VEGFR1/Flt-1 (aa 27-328) Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human VEGFR1/Flt-1 (aa 27-328) Fc Chimera, CF has been validated for the following applications: Bioactivity.
target :
VEGFR1/Flt-1
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
75-85 kDa, reducing conditions
theoretical molecular weight :
60.7 kDa (monomer)
gene symbol :
FLT1
details of functionality :
Measured by its ability to inhibit the VEGF-dependent proliferation of HUVEC human umbilical vein endothelial cells. Conn, G. et al . (1990) Proc. Natl. Acad. Sci. USA 87 :1323. The ED50 for this effect is 3-15 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P17948
applications :
Bioactivity
source :
NS0-derived Recombinant Human VEGFR1/Flt-1 (aa 27-328) Fc Chimera
USD :
458 USD
alt names :
EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.