Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF | R&D Systems 351-FS-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF

catalog :

351-FS-010/CF

quantity :

10 ug (also 50 ug)

price :

259 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Jansen J, Reimer K, Nagai J, Varghese F, Overheul G, de Beer M, et al. SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. Cell Stem Cell. 2022;29:217-231.e8 pubmed publisher
Lim J, Heo J, Ju H, Shin J, Kim Y, Lee S, et al. Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway. Sci Adv. 2020;6:eaba1334 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Wei L, Kanbe K, Lee M, Wei X, Pei M, Sun X, et al. Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation. Dev Biol. 2010;341:236-45 pubmed publisher
Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed publisher
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Ohab J, Fleming S, Blesch A, Carmichael S. A neurovascular niche for neurogenesis after stroke. J Neurosci. 2006;26:13007-16 pubmed
Muller A, Sonkoly E, Eulert C, Gerber P, Kubitza R, Schirlau K, et al. Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy. Int J Cancer. 2006;118:2147-57 pubmed
de Lavareille A, Roufosse F, Schandene L, Stordeur P, Cogan E, Goldman M. Clonal Th2 cells associated with chronic hypereosinophilia: TARC-induced CCR4 down-regulation in vivo. Eur J Immunol. 2001;31:1037-46 pubmed

product information

brand :

R&D Systems

master code :

351-FS/CF

SKU :

351-FS-010/CF

product name :

Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF

description :

The Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF from R&D Systems is derived from E. coli. The Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF has been validated for the following applications: Bioactivity.

target :

CXCL12/SDF-1 beta

category :

Proteins and Enzymes

unit sizes :

10 ug (also 50 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human, Feline

theoretical molecular weight :

8 kDa

gene symbol :

CXCL12

details of functionality :

Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED50 for this effect is 10-30 ng/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR4. The ED50 for this effect is 0.3-1.5 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P48061

applications :

Bioactivity

source :

E. coli-derived Recombinant Human/Feline CXCL12/SDF-1 beta (aa 22-93), CF

USD :

259 USD

alt names :

hSDF-1beta, PBSF, SDF 1beta, SDF1, SDF-1, SDF1 beta, SDF1b

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage