Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF | R&D Systems 3485-AN-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF

catalog :

3485-AN-050

quantity :

50 ug

price :

468 USD

citations: 7

Reference
Gleason C, Dickson M, Klein Dooley M, Antonescu C, Gularte M xe9 rida R, Benitez M, et al. Therapy-induced senescence contributes to the efficacy of abemaciclib in patients with dedifferentiated liposarcoma. Clin Cancer Res. 2023;: pubmed publisher
Hefni E, Menon D, Ma T, Asiedu E, Sultan A, Meiller T, et al. Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway. Cell Signal. 2023;108:110697 pubmed publisher
van der Kolk B, Vink R, Jocken J, Roumans N, Goossens G, Mariman E, et al. Effect of diet-induced weight loss on angiopoietin-like protein 4 and adipose tissue lipid metabolism in overweight and obese humans. Physiol Rep. 2018;6:e13735 pubmed publisher
Gruppen E, Kersten S, Dullaart R. Plasma angiopoietin-like 4 is related to phospholipid transfer protein activity in diabetic and non-diabetic subjects: role of enhanced low grade inflammation. Lipids Health Dis. 2018;17:60 pubmed publisher
Baba K, Kitajima Y, Miyake S, Nakamura J, Wakiyama K, Sato H, et al. Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. Sci Rep. 2017;7:11127 pubmed publisher
Alex S, Lange K, Amolo T, Grinstead J, Haakonsson A, Szalowska E, et al. Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ. Mol Cell Biol. 2013;33:1303-16 pubmed publisher
Kersten S, Lichtenstein L, Steenbergen E, Mudde K, Hendriks H, Hesselink M, et al. Caloric restriction and exercise increase plasma ANGPTL4 levels in humans via elevated free fatty acids. Arterioscler Thromb Vasc Biol. 2009;29:969-74 pubmed publisher

product information

master code :

3485-AN

SKU :

3485-AN-050

product name :

Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF

unit size :

50 ug

description :

The Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF from R&D Systems is derived from NS0. The Recombinant Human Angiopoietin-like 4 C-Terminal Frag, CF has been validated for the following applications: Inhibition Activity.

target :

Angiopoietin-like Protein 4/ANGPTL4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

36 kDa, reducing conditions

theoretical molecular weight :

28 kDa

gene symbol :

ANGPTL4

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Angiopoietin-like 4/ANGPTL4 C-Terminal Fragment is immobilized at 1 ╡g/mL, 100 ╡L/well, the concentration of Recombinant Human LILRB2/CD85d/ILT4 Fc Chimera (Catalog # 2078-T4 ) binds with an ED50 of 70.0-350 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9BY76

applications :

Inhibition Activity

source long :

Mouse myeloma cell line, NS0-derived human Angiopoietin-like Protein 4/ANGPTL4 protein Leu165-Ser406, with a C-terminal 6-His tag

source short :

NS0

USD :

468 USD

alt names :

Angiopoietin like Protein 4, angiopoietin-like 4, Angiopoietin-like protein 4, ANGPTL4, ARP4fasting-induced adipose factor, FIAF, FIAFhepatic angiopoietin-related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, HFARPANGPTL2, NL2, peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein, PGAR, PGARangiopoietin-related protein 4, pp1158, PPARG angiopoietin related protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.