Recombinant Mouse MMP-12 Protein, CF | R&D Systems 3467-MPB-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse MMP-12 Protein, CF

catalog :

3467-MPB-020

quantity :

20 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Jiang L, Yang M, He S, Li Z, Li H, Niu T, et al. MMP12 knockout prevents weight and muscle loss in tumor-bearing mice. BMC Cancer. 2021;21:1297 pubmed publisher
Andrault P, Panwar P, Mackenzie N, Bromme D. Elastolytic activity of cysteine cathepsins K, S, and V promotes vascular calcification. Sci Rep. 2019;9:9682 pubmed publisher
Kopec A, Joshi N, Cline Fedewa H, Wojcicki A, Ray J, Sullivan B, et al. Fibrin(ogen) drives repair after acetaminophen-induced liver injury via leukocyte Î±MÎ²2 integrin-dependent upregulation of Mmp12. J Hepatol. 2017;66:787-797 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

3467-MPB

SKU :

3467-MPB-020

product name :

Recombinant Mouse MMP-12 Protein, CF

Description :

The Recombinant Mouse MMP-12 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse MMP-12 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-12

category :

Proteins and Enzymes

unit size :

20 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MES, NaCl, CaCl2, CHAPS, ZnSO4 and PEG.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

50-62 kDa, reducing conditions

theoretical molecular weight :

52 kDa

details of functionality :

Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is 100 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

EDL24933

applications :

Enzyme Activity

source :

NS0-derived Recombinant Mouse MMP-12 Protein

USD :

423 USD

alt names :

EC 3.4.24, hME, HMEEC 3.4.24.65, Macrophage elastase, macrophage metalloelastase, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12 (macrophage elastase), Matrix metalloproteinase-12, ME, MGC138506, MME, MMP12, MMP-12

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage